Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004402 | molecular_function | histone acetyltransferase activity |
A | 0005634 | cellular_component | nucleus |
A | 0006325 | biological_process | chromatin organization |
A | 0031509 | biological_process | subtelomeric heterochromatin formation |
A | 0042393 | molecular_function | histone binding |
B | 0004402 | molecular_function | histone acetyltransferase activity |
B | 0005634 | cellular_component | nucleus |
B | 0006325 | biological_process | chromatin organization |
B | 0031509 | biological_process | subtelomeric heterochromatin formation |
B | 0042393 | molecular_function | histone binding |
C | 0000786 | cellular_component | nucleosome |
C | 0003677 | molecular_function | DNA binding |
D | 0000786 | cellular_component | nucleosome |
D | 0003677 | molecular_function | DNA binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | binding site for residue ACT A 501 |
Chain | Residue |
A | ARG39 |
A | PHE247 |
A | HOH835 |
site_id | AC2 |
Number of Residues | 25 |
Details | binding site for residue CO6 A 502 |
Chain | Residue |
A | GLN248 |
A | GLY249 |
A | GLN250 |
A | GLY251 |
A | HIS252 |
A | GLY253 |
A | ALA254 |
A | ALA275 |
A | PRO278 |
A | SER279 |
A | SER281 |
A | TYR282 |
A | LYS284 |
A | LEU285 |
A | PHE288 |
A | HOH627 |
A | HOH644 |
A | HOH673 |
A | HOH864 |
A | PHE185 |
A | ILE186 |
A | VAL238 |
A | MET241 |
A | LEU242 |
A | ILE243 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue GOL A 503 |
Chain | Residue |
A | ASP196 |
A | HOH610 |
A | HOH634 |
A | HOH674 |
B | ASP193 |
B | ASP195 |
C | LYS8 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue SO4 A 504 |
Chain | Residue |
A | THR274 |
A | ALA275 |
A | PRO278 |
A | ARG286 |
A | GLN326 |
A | HIS327 |
site_id | AC5 |
Number of Residues | 31 |
Details | binding site for residue CO6 B 401 |
Chain | Residue |
B | PHE185 |
B | ILE186 |
B | VAL238 |
B | SER239 |
B | GLN240 |
B | MET241 |
B | LEU242 |
B | ILE243 |
B | GLN248 |
B | GLY249 |
B | GLN250 |
B | GLY251 |
B | HIS252 |
B | GLY253 |
B | ALA254 |
B | GLU276 |
B | ASP277 |
B | PRO278 |
B | SER279 |
B | SER281 |
B | TYR282 |
B | LYS284 |
B | LEU285 |
B | PHE288 |
B | HOH531 |
B | HOH556 |
B | HOH571 |
B | HOH572 |
B | HOH578 |
B | HOH628 |
B | HOH758 |
site_id | AC6 |
Number of Residues | 3 |
Details | binding site for residue GOL B 402 |
Chain | Residue |
B | LEU143 |
B | HIS144 |
B | THR145 |
site_id | AC7 |
Number of Residues | 7 |
Details | binding site for residue GOL B 403 |
Chain | Residue |
B | GLY140 |
B | THR141 |
B | LYS163 |
B | ALA164 |
B | ASP165 |
B | HOH587 |
B | HOH658 |
site_id | AC8 |
Number of Residues | 6 |
Details | binding site for residue SO4 B 404 |
Chain | Residue |
B | THR274 |
B | ALA275 |
B | PRO278 |
B | ARG286 |
B | HIS327 |
B | HOH623 |
Functional Information from PROSITE/UniProt
site_id | PS00047 |
Number of Residues | 5 |
Details | HISTONE_H4 Histone H4 signature. GAKRH |
Chain | Residue | Details |
C | GLY14-HIS18 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 8 |
Details | DNA_BIND: |
Chain | Residue | Details |
C | LYS16-LYS20 | |
D | LYS16-LYS20 | |
Chain | Residue | Details |
C | SER1 | |
D | SER1 | |
B | MET241 | |
B | GLN248 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | MOD_RES: Symmetric dimethylarginine; by PRMT5 and PRMT7; alternate => ECO:0000250|UniProtKB:P62806 |
Chain | Residue | Details |
C | ARG3 | |
D | ARG3 | |
Chain | Residue | Details |
C | LYS5 | |
D | LYS5 | |
Chain | Residue | Details |
C | LYS8 | |
C | LYS16 | |
D | LYS8 | |
D | LYS16 | |
Chain | Residue | Details |
C | ALA12 | |
D | ALA12 | |
Chain | Residue | Details |
C | LYS20 | |
D | LYS20 | |
site_id | SWS_FT_FI8 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447 |
Chain | Residue | Details |
C | ALA12 | |
D | ALA12 | |
site_id | SWS_FT_FI9 |
Number of Residues | 4 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 |
Chain | Residue | Details |
C | LYS20 | |
D | LYS20 | |