6VDJ
Crystal structure of ancestral apicomplexan lactate dehydrogenase with sulfate and NADH4.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue TXD A 401 |
| Chain | Residue |
| A | GLY17 |
| A | GLY85 |
| A | THR87 |
| A | ILE109 |
| A | ILE129 |
| A | THR130 |
| A | ASN131 |
| A | LEU133 |
| A | MET154 |
| A | LEU158 |
| A | HIS186 |
| A | MET18 |
| A | SO4402 |
| A | HOH504 |
| A | ILE19 |
| A | ASP39 |
| A | VAL40 |
| A | VAL41 |
| A | TYR71 |
| A | THR83 |
| A | ALA84 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ARG162 |
| A | HIS186 |
| A | GLY229 |
| A | TXD401 |
| A | HOH509 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| B | LYS88 |
| B | ARG162 |
| B | HIS186 |
