6VDD
POL domain of Pol1 from M. smegmatis complex with DNA primer-template and dNTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| D | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| D | 0006260 | biological_process | DNA replication |
| D | 0006261 | biological_process | DNA-templated DNA replication |
| D | 0008408 | molecular_function | 3'-5' exonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue DCT A 1001 |
| Chain | Residue |
| A | GLN687 |
| A | HOH1287 |
| A | HOH1301 |
| A | HOH1339 |
| A | HIS713 |
| A | ARG733 |
| A | LYS737 |
| A | TYR741 |
| A | MG1002 |
| A | HOH1146 |
| A | HOH1236 |
| A | HOH1278 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 1002 |
| Chain | Residue |
| A | DCT1001 |
| A | HOH1287 |
| A | HOH1301 |
| A | HOH1339 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1003 |
| Chain | Residue |
| A | HOH1211 |
| A | HOH1383 |
| A | HOH1419 |
| A | HOH1467 |
| A | HOH1495 |
| D | HOH1375 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1004 |
| Chain | Residue |
| A | ILE641 |
| A | HOH1205 |
| A | HOH1394 |
| A | HOH1413 |
| A | HOH1428 |
| C | HOH104 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 101 |
| Chain | Residue |
| A | HOH1146 |
| A | HOH1168 |
| A | HOH1367 |
| A | HOH1385 |
| B | DA11 |
| B | HOH221 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue DCT D 1001 |
| Chain | Residue |
| D | GLN687 |
| D | HIS713 |
| D | ARG733 |
| D | LYS737 |
| D | TYR741 |
| D | MG1002 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue MG D 1002 |
| Chain | Residue |
| D | GLN687 |
| D | DCT1001 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 1003 |
| Chain | Residue |
| D | ILE641 |
| D | HOH1182 |
| D | HOH1270 |
| D | HOH1336 |
| D | HOH1354 |
| F | HOH105 |
Functional Information from PROSITE/UniProt
| site_id | PS00447 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_A DNA polymerase family A signature. RrrVKamsYGlaYglSaygL |
| Chain | Residue | Details |
| A | ARG733-LEU752 |
