6VCS
SRA domain of UHRF1 in complex with DNA
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | HIS450 | |
| A | GLY456 | |
| B | HIS450 | |
| B | GLY456 | |
| E | HIS450 | |
| E | GLY456 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Required to confer preferential recognition of cytosine over thymine |
| Chain | Residue | Details |
| A | TYR466 | |
| B | TYR466 | |
| E | TYR466 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | SITE: Required to discriminate between hemimethylated DNA versus symmetrically methylated DNA |
| Chain | Residue | Details |
| A | PHE476 | |
| B | PHE476 | |
| E | PHE476 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | SITE: Required for affinity and specificity for 5-mCpG sequence |
| Chain | Residue | Details |
| A | TYR478 | |
| B | TYR478 | |
| E | TYR478 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | VAL533 | |
| B | VAL533 | |
| E | VAL533 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447 |
| Chain | Residue | Details |
| A | VAL533 | |
| B | VAL533 | |
| E | VAL533 |
