Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue QS7 A 801 |
| Chain | Residue |
| A | LEU473 |
| A | GLY556 |
| A | LEU619 |
| A | ALA629 |
| A | ASP630 |
| A | HOH947 |
| A | VAL481 |
| A | ARG483 |
| A | LYS503 |
| A | GLU520 |
| A | VAL550 |
| A | GLU551 |
| A | CYS552 |
| A | ALA553 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 802 |
| Chain | Residue |
| A | ARG559 |
| A | ARG616 |
| A | THR646 |
| A | SER647 |
| A | ASN648 |
| A | ARG650 |
| A | HOH979 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 803 |
| Chain | Residue |
| A | HIS727 |
| A | ALA728 |
| A | HOH932 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 31 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGCFGQVVrAeafgmdparpdqast...VAVK |
| Chain | Residue | Details |
| A | LEU473-LYS503 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
| Chain | Residue | Details |
| A | CYS608-VAL620 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"18670643","evidenceCode":"ECO:0000269"}]} |
