6V7X
Structure of a phage-encoded quorum sensing anti-activator, Aqs1 bound to LasR
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0001216 | molecular_function | DNA-binding transcription activator activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0009372 | biological_process | quorum sensing |
| B | 0010468 | biological_process | regulation of gene expression |
| B | 0032993 | cellular_component | protein-DNA complex |
| B | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| B | 0051544 | biological_process | positive regulation of elastin biosynthetic process |
| B | 0060310 | biological_process | regulation of elastin catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue OHN B 301 |
| Chain | Residue |
| B | LEU36 |
| B | ALA105 |
| B | GLY126 |
| B | SER129 |
| B | HOH406 |
| B | ILE52 |
| B | TYR56 |
| B | TRP60 |
| B | TYR64 |
| B | ASP73 |
| B | THR75 |
| B | VAL76 |
| B | TRP88 |
Functional Information from PROSITE/UniProt
| site_id | PS00622 |
| Number of Residues | 28 |
| Details | HTH_LUXR_1 LuxR-type HTH domain signature. GktSweISviCnCseaNVnfHmgNIrrK |
| Chain | Residue | Details |
| B | GLY191-LYS218 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 19 |
| Details | DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00411 |
| Chain | Residue | Details |
| B | SER194-GLY213 |
