Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0007596 | biological_process | blood coagulation |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0006508 | biological_process | proteolysis |
| B | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 101 |
| Chain | Residue |
| A | TYR14 |
| A | TYR14 |
| A | HOH203 |
| A | HOH203 |
| B | TYR134 |
| B | TYR134 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue 0G6 B 301 |
| Chain | Residue |
| B | GLU97 |
| B | LEU99 |
| B | ASP189 |
| B | ALA190 |
| B | GLY193 |
| B | SER195 |
| B | SER214 |
| B | FTR215 |
| B | GLY216 |
| B | GLY219 |
| B | CYS220 |
| B | GLY226 |
| B | LYS236 |
| B | HOH405 |
| B | HOH425 |
| B | HOH435 |
| B | HOH448 |
| B | HIS57 |
| B | TYR60 |
| B | FTR60 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 302 |
| Chain | Residue |
| B | ARG221 |
| B | LYS224 |
| B | HOH406 |
| B | HOH427 |
| B | HOH434 |
| B | HOH462 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| B | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAceGDSGGPFV |
| Chain | Residue | Details |
| B | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| B | HIS57 | |
| B | ASP102 | |
| B | SER195 | |
| Chain | Residue | Details |
| B | ASN60 | |
