6V4S
A Closed pore conformation of a Pentameic ligand-gated ion channel with additional N-terminal domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004888 | molecular_function | transmembrane signaling receptor activity |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0004888 | molecular_function | transmembrane signaling receptor activity |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| C | 0004888 | molecular_function | transmembrane signaling receptor activity |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0016020 | cellular_component | membrane |
| C | 0034220 | biological_process | monoatomic ion transmembrane transport |
| D | 0004888 | molecular_function | transmembrane signaling receptor activity |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0016020 | cellular_component | membrane |
| D | 0034220 | biological_process | monoatomic ion transmembrane transport |
| E | 0004888 | molecular_function | transmembrane signaling receptor activity |
| E | 0005216 | molecular_function | monoatomic ion channel activity |
| E | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| E | 0006811 | biological_process | monoatomic ion transport |
| E | 0016020 | cellular_component | membrane |
| E | 0034220 | biological_process | monoatomic ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 703 |
| Chain | Residue |
| A | GLU547 |
| C | GLU547 |
| D | GLU547 |
| E | GLU547 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 705 |
| Chain | Residue |
| A | ARG345 |
| E | GLU481 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 706 |
| Chain | Residue |
| A | ASN560 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue LMT A 707 |
| Chain | Residue |
| B | PHE635 |
| A | ASN514 |
| A | GLU516 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CA E 701 |
| Chain | Residue |
| D | GLU479 |
| E | GLU347 |
| E | PRO434 |
| E | PHE436 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue CL E 702 |
| Chain | Residue |
| E | ASN560 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue LMT E 703 |
| Chain | Residue |
| A | ARG634 |
| E | GLU480 |
| E | GLU516 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue LMT E 704 |
| Chain | Residue |
| D | GLU516 |
| E | ARG634 |
| E | PHE635 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue LMT E 705 |
| Chain | Residue |
| E | PHE538 |
| E | THR614 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue NA D 701 |
| Chain | Residue |
| D | GLU481 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue CL D 702 |
| Chain | Residue |
| D | ASN560 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue LMT D 703 |
| Chain | Residue |
| D | LYS540 |
| D | THR614 |
| E | ARG599 |
| E | VAL603 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue CL C 704 |
| Chain | Residue |
| C | ASN560 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue LMT C 705 |
| Chain | Residue |
| C | GLU516 |
| D | ARG634 |
| D | PHE635 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue LMT C 706 |
| Chain | Residue |
| C | THR614 |
| D | ARG599 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue NA B 702 |
| Chain | Residue |
| B | GLU481 |
| C | ARG345 |
| site_id | AD8 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 703 |
| Chain | Residue |
| B | ASN560 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue LMT B 704 |
| Chain | Residue |
| B | GLU516 |
| C | ARG634 |
| C | PHE635 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue LMT B 705 |
| Chain | Residue |
| B | LYS540 |
| B | THR614 |
| C | ARG599 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue LMT B 706 |
| Chain | Residue |
| A | PHE538 |
| A | LYS540 |
| A | THR614 |
| B | ARG599 |
