6V1H
Crystal structure of the bromodomain of human BRD7 bound to bromosporine
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue BMF A 301 |
| Chain | Residue |
| A | ALA154 |
| A | TYR217 |
| A | HOH403 |
| A | PHE155 |
| A | SER157 |
| A | PHE158 |
| A | VAL160 |
| A | PHE163 |
| A | ILE164 |
| A | ALA207 |
| A | ASN211 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | LYS150 |
| A | SER227 |
| A | LYS230 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS186 | |
| A | LYS197 | |
| A | LYS201 | |
| A | LYS212 | |
| A | LYS241 |
