6V1E
Crystal structure of the bromodomain of human BRD7 bound to BI7273
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 5SW A 301 |
| Chain | Residue |
| A | SER153 |
| A | ASN211 |
| A | TYR217 |
| A | HOH413 |
| A | ALA154 |
| A | PHE155 |
| A | PHE156 |
| A | PHE158 |
| A | PRO159 |
| A | VAL160 |
| A | PHE163 |
| A | ILE164 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | ILE171 |
| A | ILE172 |
| A | LYS173 |
| A | HIS174 |
| A | LEU202 |
| A | ASN206 |
| A | GLU235 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
