6UXI
Structure of serine hydroxymethyltransferase 8 from Glycine max cultivar Essex complexed with PLP-Glycine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| A | 0019264 | biological_process | glycine biosynthetic process from serine |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0035999 | biological_process | tetrahydrofolate interconversion |
| B | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| B | 0019264 | biological_process | glycine biosynthetic process from serine |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0035999 | biological_process | tetrahydrofolate interconversion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue PLG A 701 |
| Chain | Residue |
| A | SER39 |
| A | HIS218 |
| A | THR241 |
| A | HIS243 |
| A | LYS244 |
| A | ARG389 |
| B | TYR59 |
| B | TYR104 |
| B | GLY289 |
| B | GLY290 |
| B | HOH959 |
| A | SER105 |
| A | GLY106 |
| A | SER107 |
| A | HIS134 |
| A | GLY189 |
| A | SER190 |
| A | ASP215 |
| A | ALA217 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 702 |
| Chain | Residue |
| A | ILE48 |
| A | GLU49 |
| A | GLY52 |
| A | HOH819 |
| B | GLY52 |
| B | HOH973 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | binding site for residue PLG B 801 |
| Chain | Residue |
| A | TYR59 |
| A | GLY289 |
| A | GLY290 |
| B | SER39 |
| B | SER105 |
| B | GLY106 |
| B | SER107 |
| B | HIS134 |
| B | GLY189 |
| B | SER190 |
| B | ASP215 |
| B | ALA217 |
| B | HIS218 |
| B | THR241 |
| B | HIS243 |
| B | LYS244 |
| B | ARG389 |
| B | HOH984 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 802 |
| Chain | Residue |
| A | LYS176 |
| A | ASP179 |
| B | LYS176 |
| B | ASP179 |
Functional Information from PROSITE/UniProt
| site_id | PS00096 |
| Number of Residues | 17 |
| Details | SHMT Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. DIvTTTTHKSLrGPRAG |
| Chain | Residue | Details |
| A | ASP236-GLY252 |
