Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
| C | 0042981 | biological_process | regulation of apoptotic process |
| D | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | TYR120 |
| A | PHE123 |
| A | GLU124 |
| A | TRP169 |
| A | HOH418 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| C | ARG103 |
| C | QHJ301 |
| A | ARG165 |
| A | ALA168 |
| A | THR172 |
| A | HOH414 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue QHJ A 303 |
| Chain | Residue |
| A | ALA93 |
| A | TYR101 |
| A | ALA104 |
| A | PHE105 |
| A | LEU108 |
| A | LEU130 |
| A | ASN136 |
| A | GLY138 |
| A | ARG139 |
| A | ALA142 |
| A | SER145 |
| A | PHE191 |
| A | HOH404 |
| C | ARG165 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue QHJ B 301 |
| Chain | Residue |
| B | ALA93 |
| B | GLU96 |
| B | PHE97 |
| B | TYR101 |
| B | PHE105 |
| B | LEU108 |
| B | GLU129 |
| B | ASN136 |
| B | GLY138 |
| B | ARG139 |
| B | ALA142 |
| B | PHE191 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residue QHJ C 301 |
| Chain | Residue |
| A | ARG165 |
| A | SO4302 |
| C | ALA93 |
| C | TYR101 |
| C | PHE105 |
| C | GLU129 |
| C | LEU130 |
| C | ASN136 |
| C | GLY138 |
| C | ARG139 |
| C | ALA142 |
| C | PHE191 |
| C | TYR195 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 301 |
| Chain | Residue |
| A | ARG100 |
| D | GLN160 |
| D | VAL161 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue QHJ D 302 |
| Chain | Residue |
| B | GLN111 |
| B | HIS113 |
| D | ALA93 |
| D | PHE97 |
| D | ARG100 |
| D | TYR101 |
| D | ALA104 |
| D | PHE105 |
| D | LEU108 |
| D | LEU130 |
| D | ASN136 |
| D | TRP137 |
| D | GLY138 |
| D | ALA142 |
| D | PHE146 |
| D | PHE191 |
| D | TYR195 |
| D | HOH405 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 19 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG |
| Chain | Residue | Details |
| A | LEU130-GLY148 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV |
| Chain | Residue | Details |
| A | TRP181-VAL192 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR |
| Chain | Residue | Details |
| A | VAL86-ARG100 | |
| site_id | PS01260 |
| Number of Residues | 21 |
| Details | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW |
| Chain | Residue | Details |
| A | SER4-TRP24 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; by caspase-1 |
| Chain | Residue | Details |
| A | GLY117 | |
| B | GLY117 | |
| C | GLY117 | |
| D | GLY117 | |
| Chain | Residue | Details |
| A | PHE105 | |
| B | PHE105 | |
| C | PHE105 | |
| D | PHE105 | |
| Chain | Residue | Details |
| A | THR118 | |
| B | THR118 | |
| C | THR118 | |
| D | THR118 | |
