6USV
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and SDZ 220-040
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GLY A 901 |
| Chain | Residue |
| A | PHE92 |
| A | PRO124 |
| A | THR126 |
| A | ARG131 |
| A | SER179 |
| A | SER180 |
| A | ASP224 |
| A | PHE250 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue QGP B 301 |
| Chain | Residue |
| B | HIS88 |
| B | SER114 |
| B | LEU115 |
| B | THR116 |
| B | ARG121 |
| B | GLY172 |
| B | SER173 |
| B | THR174 |
| B | TYR214 |
| B | VAL218 |
| B | TYR245 |
| B | GOL302 |
| B | HOH403 |
| B | HOH404 |
| B | HOH405 |
| B | GLU16 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 302 |
| Chain | Residue |
| B | GLU16 |
| B | HIS88 |
| B | QGP301 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16281028, ECO:0007744|PDB:2A5S, ECO:0007744|PDB:2A5T, ECO:0007744|PDB:4NF4, ECO:0007744|PDB:4NF8, ECO:0007744|PDB:5I56, ECO:0007744|PDB:5I57, ECO:0007744|PDB:5I58, ECO:0007744|PDB:5I59, ECO:0007744|PDB:5JTY |
| Chain | Residue | Details |
| B | SER114 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16281028, ECO:0000269|PubMed:24462099, ECO:0000269|PubMed:27618671, ECO:0007744|PDB:2A5S, ECO:0007744|PDB:2A5T, ECO:0007744|PDB:4NF4, ECO:0007744|PDB:4NF8, ECO:0007744|PDB:5I56, ECO:0007744|PDB:5I57, ECO:0007744|PDB:5I58, ECO:0007744|PDB:5I59, ECO:0007744|PDB:5JTY |
| Chain | Residue | Details |
| B | ARG121 | |
| A | ILE159 | |
| A | TYR203 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16281028, ECO:0000269|PubMed:24462099, ECO:0007744|PDB:2A5S, ECO:0007744|PDB:2A5T, ECO:0007744|PDB:4NF4, ECO:0007744|PDB:4NF8 |
| Chain | Residue | Details |
| B | SER173 | |
| B | TYR214 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN46 | |
| B | ASN47 | |
| B | ASN171 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0007744|PubMed:24090084 |
| Chain | Residue | Details |
| A | GLY242 |
