6US8
Influenza A M2 proton channel wild type TM domain bound to S-rimantadine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015078 | molecular_function | proton transmembrane transporter activity |
| A | 0033644 | cellular_component | host cell membrane |
| A | 0055036 | cellular_component | virion membrane |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0015078 | molecular_function | proton transmembrane transporter activity |
| B | 0033644 | cellular_component | host cell membrane |
| B | 0055036 | cellular_component | virion membrane |
| B | 1902600 | biological_process | proton transmembrane transport |
| C | 0015078 | molecular_function | proton transmembrane transporter activity |
| C | 0033644 | cellular_component | host cell membrane |
| C | 0055036 | cellular_component | virion membrane |
| C | 1902600 | biological_process | proton transmembrane transport |
| D | 0015078 | molecular_function | proton transmembrane transporter activity |
| D | 0033644 | cellular_component | host cell membrane |
| D | 0055036 | cellular_component | virion membrane |
| D | 1902600 | biological_process | proton transmembrane transport |
| E | 0015078 | molecular_function | proton transmembrane transporter activity |
| E | 0033644 | cellular_component | host cell membrane |
| E | 0055036 | cellular_component | virion membrane |
| E | 1902600 | biological_process | proton transmembrane transport |
| F | 0015078 | molecular_function | proton transmembrane transporter activity |
| F | 0033644 | cellular_component | host cell membrane |
| F | 0055036 | cellular_component | virion membrane |
| F | 1902600 | biological_process | proton transmembrane transport |
| G | 0015078 | molecular_function | proton transmembrane transporter activity |
| G | 0033644 | cellular_component | host cell membrane |
| G | 0055036 | cellular_component | virion membrane |
| G | 1902600 | biological_process | proton transmembrane transport |
| H | 0015078 | molecular_function | proton transmembrane transporter activity |
| H | 0033644 | cellular_component | host cell membrane |
| H | 0055036 | cellular_component | virion membrane |
| H | 1902600 | biological_process | proton transmembrane transport |
| I | 0015078 | molecular_function | proton transmembrane transporter activity |
| I | 0033644 | cellular_component | host cell membrane |
| I | 0055036 | cellular_component | virion membrane |
| I | 1902600 | biological_process | proton transmembrane transport |
| J | 0015078 | molecular_function | proton transmembrane transporter activity |
| J | 0033644 | cellular_component | host cell membrane |
| J | 0055036 | cellular_component | virion membrane |
| J | 1902600 | biological_process | proton transmembrane transport |
| K | 0015078 | molecular_function | proton transmembrane transporter activity |
| K | 0033644 | cellular_component | host cell membrane |
| K | 0055036 | cellular_component | virion membrane |
| K | 1902600 | biological_process | proton transmembrane transport |
| L | 0015078 | molecular_function | proton transmembrane transporter activity |
| L | 0033644 | cellular_component | host cell membrane |
| L | 0055036 | cellular_component | virion membrane |
| L | 1902600 | biological_process | proton transmembrane transport |
| M | 0015078 | molecular_function | proton transmembrane transporter activity |
| M | 0033644 | cellular_component | host cell membrane |
| M | 0055036 | cellular_component | virion membrane |
| M | 1902600 | biological_process | proton transmembrane transport |
| N | 0015078 | molecular_function | proton transmembrane transporter activity |
| N | 0033644 | cellular_component | host cell membrane |
| N | 0055036 | cellular_component | virion membrane |
| N | 1902600 | biological_process | proton transmembrane transport |
| O | 0015078 | molecular_function | proton transmembrane transporter activity |
| O | 0033644 | cellular_component | host cell membrane |
| O | 0055036 | cellular_component | virion membrane |
| O | 1902600 | biological_process | proton transmembrane transport |
| P | 0015078 | molecular_function | proton transmembrane transporter activity |
| P | 0033644 | cellular_component | host cell membrane |
| P | 0055036 | cellular_component | virion membrane |
| P | 1902600 | biological_process | proton transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 101 |
| Chain | Residue |
| A | HOH102 |
| B | HOH209 |
| C | HOH103 |
| D | HOH103 |
| D | HOH104 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue EU7 B 102 |
| Chain | Residue |
| B | HOH201 |
| B | HOH203 |
| B | HOH204 |
| B | HOH207 |
| B | HOH208 |
| C | SER31 |
| D | ALA30 |
| D | SER31 |
| D | GLY34 |
| A | ALA30 |
| A | SER31 |
| A | GLY34 |
| B | SER31 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EU7 B 103 |
| Chain | Residue |
| B | ARG45 |
| G | VAL28 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CL E 101 |
| Chain | Residue |
| E | HOH209 |
| E | HOH210 |
| F | HOH103 |
| G | HOH103 |
| H | HOH204 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residue EU7 E 102 |
| Chain | Residue |
| E | ALA30 |
| E | SER31 |
| E | HOH201 |
| E | HOH202 |
| E | HOH204 |
| E | HOH205 |
| E | HOH206 |
| F | ALA30 |
| F | GLY34 |
| G | GLY34 |
| H | ALA30 |
| H | SER31 |
| H | GLY34 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EU7 H 101 |
| Chain | Residue |
| E | LEU46 |
| H | ASP44 |
| I | ILE32 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EU7 J 101 |
| Chain | Residue |
| I | ASP44 |
| J | TRP41 |
| J | ARG45 |
| J | LEU46 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CL K 101 |
| Chain | Residue |
| I | HOH105 |
| J | HOH201 |
| J | HOH203 |
| K | HOH202 |
| K | HOH206 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue EU7 L 101 |
| Chain | Residue |
| I | ALA30 |
| I | SER31 |
| I | GLY34 |
| J | SER31 |
| K | SER31 |
| L | ALA30 |
| L | SER31 |
| L | HOH201 |
| L | HOH202 |
| L | HOH203 |
| L | HOH205 |
| L | HOH206 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue EU7 L 102 |
| Chain | Residue |
| K | ASP44 |
| L | ARG45 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue EU7 L 103 |
| Chain | Residue |
| J | VAL28 |
| L | ASP44 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue CL M 101 |
| Chain | Residue |
| M | HOH208 |
| N | HOH206 |
| O | HOH202 |
| P | HOH103 |
| site_id | AD4 |
| Number of Residues | 13 |
| Details | binding site for residue EU7 M 102 |
| Chain | Residue |
| M | SER31 |
| M | HOH201 |
| M | HOH202 |
| M | HOH203 |
| M | HOH204 |
| M | HOH209 |
| N | GLY34 |
| O | ALA30 |
| O | SER31 |
| O | GLY34 |
| P | ALA30 |
| P | SER31 |
| P | GLY34 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EU7 M 103 |
| Chain | Residue |
| M | LEU26 |
| M | TRP41 |
| M | ARG45 |
| N | VAL28 |
| N | ILE32 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EU7 N 101 |
| Chain | Residue |
| M | ASP44 |
| N | TRP41 |
| N | ARG45 |
| N | LEU46 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue EU7 O 101 |
| Chain | Residue |
| F | ASP44 |
| G | LEU46 |
| O | VAL28 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide LEU B 46 and NH2 B 47 |
| Chain | Residue |
| B | ILE42 |
| B | LEU43 |
| B | ASP44 |
| B | ARG45 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide LEU C 46 and NH2 C 47 |
| Chain | Residue |
| C | ILE42 |
| C | LEU43 |
| C | ASP44 |
| C | ARG45 |
| D | SER23 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide LEU D 46 and NH2 D 47 |
| Chain | Residue |
| D | ILE42 |
| D | LEU43 |
| D | ASP44 |
| D | ARG45 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide LEU E 46 and NH2 E 47 |
| Chain | Residue |
| E | ILE42 |
| E | LEU43 |
| E | ASP44 |
| E | ARG45 |
| H | EU7101 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide LEU F 46 and NH2 F 47 |
| Chain | Residue |
| F | ILE42 |
| F | LEU43 |
| F | ASP44 |
| F | ARG45 |
| N | PRO25 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for Di-peptide LEU G 46 and NH2 G 47 |
| Chain | Residue |
| G | ILE42 |
| G | LEU43 |
| G | ASP44 |
| G | ARG45 |
| H | SER23 |
| O | EU7101 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide LEU H 46 and NH2 H 47 |
| Chain | Residue |
| H | ILE42 |
| H | LEU43 |
| H | ASP44 |
| H | ARG45 |
| L | PRO25 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide LEU I 46 and NH2 I 47 |
| Chain | Residue |
| I | ILE42 |
| I | LEU43 |
| I | ASP44 |
| I | ARG45 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide LEU J 46 and NH2 J 47 |
| Chain | Residue |
| J | ILE42 |
| J | LEU43 |
| J | ASP44 |
| J | ARG45 |
| J | EU7101 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide LEU K 46 and NH2 K 47 |
| Chain | Residue |
| A | PRO25 |
| K | ILE42 |
| K | LEU43 |
| K | ASP44 |
| K | ARG45 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide LEU L 46 and NH2 L 47 |
| Chain | Residue |
| I | PRO25 |
| L | ILE42 |
| L | LEU43 |
| L | ASP44 |
| L | ARG45 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide LEU M 46 and NH2 M 47 |
| Chain | Residue |
| C | PRO25 |
| M | ILE42 |
| M | LEU43 |
| M | ASP44 |
| M | ARG45 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide LEU N 46 and NH2 N 47 |
| Chain | Residue |
| N | ILE42 |
| N | LEU43 |
| N | ASP44 |
| N | ARG45 |
| N | EU7101 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide LEU O 46 and NH2 O 47 |
| Chain | Residue |
| O | ILE42 |
| O | LEU43 |
| O | ASP44 |
| O | ARG45 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide LEU P 46 and NH2 P 47 |
| Chain | Residue |
| M | PRO25 |
| P | ILE42 |
| P | LEU43 |
| P | ASP44 |
| P | ARG45 |
