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6UPH

Structure of a Yeast Centromeric Nucleosome at 2.7 Angstrom resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0000070biological_processmitotic sister chromatid segregation
A0000278biological_processmitotic cell cycle
A0000775cellular_componentchromosome, centromeric region
A0000779cellular_componentcondensed chromosome, centromeric region
A0000786cellular_componentnucleosome
A0003677molecular_functionDNA binding
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005694cellular_componentchromosome
A0005729cellular_component2-micrometer circle DNA
A0005777cellular_componentperoxisome
A0009303biological_processrRNA transcription
A0019237molecular_functioncentromeric DNA binding
A0030527molecular_functionstructural constituent of chromatin
A0030543biological_process2-micrometer plasmid partitioning
A0032991cellular_componentprotein-containing complex
A0043505cellular_componentCENP-A containing nucleosome
A0043565molecular_functionsequence-specific DNA binding
A0046982molecular_functionprotein heterodimerization activity
A0051382biological_processkinetochore assembly
A0061644biological_processprotein localization to CENP-A containing chromatin
B0000786cellular_componentnucleosome
B0003677molecular_functionDNA binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005694cellular_componentchromosome
B0006334biological_processnucleosome assembly
B0030527molecular_functionstructural constituent of chromatin
B0043505cellular_componentCENP-A containing nucleosome
B0046982molecular_functionprotein heterodimerization activity
C0000786cellular_componentnucleosome
C0003677molecular_functionDNA binding
C0005634cellular_componentnucleus
C0005694cellular_componentchromosome
C0006281biological_processDNA repair
C0030527molecular_functionstructural constituent of chromatin
C0043505cellular_componentCENP-A containing nucleosome
C0046982molecular_functionprotein heterodimerization activity
D0000786cellular_componentnucleosome
D0003677molecular_functionDNA binding
D0005634cellular_componentnucleus
D0005694cellular_componentchromosome
D0030527molecular_functionstructural constituent of chromatin
D0043505cellular_componentCENP-A containing nucleosome
D0046982molecular_functionprotein heterodimerization activity
E0000070biological_processmitotic sister chromatid segregation
E0000278biological_processmitotic cell cycle
E0000775cellular_componentchromosome, centromeric region
E0000779cellular_componentcondensed chromosome, centromeric region
E0000786cellular_componentnucleosome
E0003677molecular_functionDNA binding
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005694cellular_componentchromosome
E0005729cellular_component2-micrometer circle DNA
E0005777cellular_componentperoxisome
E0009303biological_processrRNA transcription
E0019237molecular_functioncentromeric DNA binding
E0030527molecular_functionstructural constituent of chromatin
E0030543biological_process2-micrometer plasmid partitioning
E0032991cellular_componentprotein-containing complex
E0043505cellular_componentCENP-A containing nucleosome
E0043565molecular_functionsequence-specific DNA binding
E0046982molecular_functionprotein heterodimerization activity
E0051382biological_processkinetochore assembly
E0061644biological_processprotein localization to CENP-A containing chromatin
F0000786cellular_componentnucleosome
F0003677molecular_functionDNA binding
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005694cellular_componentchromosome
F0006334biological_processnucleosome assembly
F0030527molecular_functionstructural constituent of chromatin
F0043505cellular_componentCENP-A containing nucleosome
F0046982molecular_functionprotein heterodimerization activity
G0000786cellular_componentnucleosome
G0003677molecular_functionDNA binding
G0005634cellular_componentnucleus
G0005694cellular_componentchromosome
G0006281biological_processDNA repair
G0030527molecular_functionstructural constituent of chromatin
G0043505cellular_componentCENP-A containing nucleosome
G0046982molecular_functionprotein heterodimerization activity
H0000786cellular_componentnucleosome
H0003677molecular_functionDNA binding
H0005634cellular_componentnucleus
H0005694cellular_componentchromosome
H0030527molecular_functionstructural constituent of chromatin
H0043505cellular_componentCENP-A containing nucleosome
H0046982molecular_functionprotein heterodimerization activity
Functional Information from PROSITE/UniProt
site_idPS00047
Number of Residues5
DetailsHISTONE_H4 Histone H4 signature. GAKRH
ChainResidueDetails
BGLY15-HIS19

site_idPS00014
Number of Residues4
DetailsER_TARGET Endoplasmic reticulum targeting sequence. SQEL
ChainResidueDetails
CSER127-LEU130

site_idPS00046
Number of Residues7
DetailsHISTONE_H2A Histone H2A signature. AGLtFPV
ChainResidueDetails
CALA22-VAL28

site_idPS00357
Number of Residues23
DetailsHISTONE_H2B Histone H2B signature. REIQTavRlILpGELaKHAVSEG
ChainResidueDetails
DARG97-GLY119

site_idPS00959
Number of Residues9
DetailsHISTONE_H3_2 Histone H3 signature 2. PFaRLVKEV
ChainResidueDetails
APRO157-VAL165

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsMOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P02293
ChainResidueDetails
DLYS7
DLYS17
HLYS7
HLYS17

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P02293
ChainResidueDetails
DSER11
HSER11
GLYS4
GLYS7

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P02293
ChainResidueDetails
DLYS12
HLYS12

site_idSWS_FT_FI4
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO); alternate => ECO:0000250|UniProtKB:P02293
ChainResidueDetails
DLYS7
DLYS17
HLYS7
HLYS17

site_idSWS_FT_FI5
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P02293
ChainResidueDetails
DLYS125
HLYS125

site_idSWS_FT_FI6
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000250|UniProtKB:P02293
ChainResidueDetails
DLYS18
HLYS18

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PDB entries from 2024-05-01

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