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6UP3

Crystal structure of the murine DHX36 helicase in complex with ANP

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0005524molecular_functionATP binding
Functional Information from PDB Data
site_idAC1
Number of Residues17
Detailsbinding site for residue ANP A 1001
ChainResidue
AGLY225
APHE529
ATHR548
ASER549
ATHR551
AASP553
AARG597
AHOH1103
AHOH1105
ACYS226
AGLY227
ALYS228
ATHR229
ATHR230
AARG267
AASP326
AGLU327

Functional Information from PROSITE/UniProt
site_idPS00690
Number of Residues10
DetailsDEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. ShIVLDEIHE
ChainResidueDetails
ASER321-GLU330

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues5
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q05B79
ChainResidueDetails
AGLY225
AGLU327
AHIS329
ASER549
AARG594

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9H2U1
ChainResidueDetails
ASER153
ASER955

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q9H2U1
ChainResidueDetails
ALYS939

226707

PDB entries from 2024-10-30

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