6UEE
Pseudomonas aeruginosa LpxA Complex Structure with Ligand
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008610 | biological_process | lipid biosynthetic process |
| A | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| A | 0009245 | biological_process | lipid A biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008610 | biological_process | lipid biosynthetic process |
| B | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| B | 0009245 | biological_process | lipid A biosynthetic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008610 | biological_process | lipid biosynthetic process |
| C | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| C | 0009245 | biological_process | lipid A biosynthetic process |
| C | 0016020 | cellular_component | membrane |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008610 | biological_process | lipid biosynthetic process |
| D | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| D | 0009245 | biological_process | lipid A biosynthetic process |
| D | 0016020 | cellular_component | membrane |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0008610 | biological_process | lipid biosynthetic process |
| E | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| E | 0009245 | biological_process | lipid A biosynthetic process |
| E | 0016020 | cellular_component | membrane |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016746 | molecular_function | acyltransferase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0008610 | biological_process | lipid biosynthetic process |
| F | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| F | 0009245 | biological_process | lipid A biosynthetic process |
| F | 0016020 | cellular_component | membrane |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016746 | molecular_function | acyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue Q5M A 301 |
| Chain | Residue |
| A | HIS118 |
| C | MET169 |
| A | ALA138 |
| A | HIS156 |
| A | GLN157 |
| A | HOH415 |
| C | VAL132 |
| C | ASN133 |
| C | SER150 |
| C | GLY151 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue Q5M A 302 |
| Chain | Residue |
| A | LEU3 |
| A | ASP5 |
| A | VAL22 |
| A | GLY23 |
| A | PRO24 |
| A | VAL39 |
| A | GLY41 |
| A | PRO42 |
| A | ARG57 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ARG246 |
| A | ASP247 |
| A | GLN250 |
| F | GLU31 |
| F | GLU33 |
| F | THR50 |
| F | LYS51 |
| F | ARG79 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue Q5M A 304 |
| Chain | Residue |
| A | MET114 |
| A | VAL132 |
| A | ASN133 |
| A | SER150 |
| A | GLY151 |
| A | PHE166 |
| B | ALA136 |
| B | ALA138 |
| B | HIS156 |
| B | HOH625 |
| B | HOH654 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 501 |
| Chain | Residue |
| B | PRO42 |
| B | ARG57 |
| B | GLN60 |
| C | VAL45 |
| C | GLU66 |
| C | HOH412 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 502 |
| Chain | Residue |
| B | ASP144 |
| B | ASP145 |
| B | ALA163 |
| B | HOH601 |
| B | HOH621 |
| D | GLN100 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue Q5M C 301 |
| Chain | Residue |
| B | VAL132 |
| B | ASN133 |
| B | SER150 |
| B | GLY151 |
| B | MET169 |
| C | HIS118 |
| C | ALA138 |
| C | HIS156 |
| C | GLN157 |
| C | HOH437 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 302 |
| Chain | Residue |
| C | PHE166 |
| C | ASN194 |
| C | PHE195 |
| C | GLU196 |
| C | HOH425 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residue Q5M D 301 |
| Chain | Residue |
| D | VAL132 |
| D | ASN133 |
| D | SER150 |
| D | GLY151 |
| D | PHE166 |
| D | MET169 |
| D | HOH405 |
| D | HOH437 |
| D | HOH450 |
| F | ALA138 |
| F | HOH348 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for residue Q5M E 301 |
| Chain | Residue |
| D | HIS118 |
| D | ALA138 |
| D | GLN157 |
| E | VAL132 |
| E | ASN133 |
| E | SER150 |
| E | GLY151 |
| E | PHE166 |
| E | MET169 |
| E | HOH427 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue Q5M E 302 |
| Chain | Residue |
| E | ALA136 |
| E | ALA138 |
| E | HIS156 |
| E | GLN157 |
| F | VAL132 |
| F | ASN133 |
| F | SER150 |
| F | GLY151 |
| F | MET169 |
| site_id | AD3 |
| Number of Residues | 10 |
| Details | binding site for residue Q5M E 303 |
| Chain | Residue |
| B | GLY255 |
| B | ILE256 |
| B | ARG258 |
| E | LEU3 |
| E | ALA18 |
| E | HOH429 |
| B | VAL225 |
| B | GLU226 |
| B | ILE249 |
| B | ALA252 |
Functional Information from PROSITE/UniProt
| site_id | PS00101 |
| Number of Residues | 29 |
| Details | HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IDprAiIdpsArLAadVqVGpwSiVgaeV |
| Chain | Residue | Details |
| A | ILE4-VAL32 |
