6U8H
BRD2-BD1 in complex with the cyclic peptide 3.2_2
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 201 |
| Chain | Residue |
| A | TRP97 |
| A | TRP97 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 204 |
| Chain | Residue |
| A | HIS93 |
| A | GLN94 |
| A | TRP97 |
| A | ARG100 |
| A | HOH328 |
| C | LYS6 |
| C | PE3105 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 205 |
| Chain | Residue |
| A | GLN101 |
| A | PRO102 |
| A | ASP104 |
| A | LYS107 |
| A | HOH375 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue NH2 C 101 |
| Chain | Residue |
| C | ASN9 |
| C | LEU10 |
| C | ILE11 |
| C | HIS12 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue IOD C 102 |
| Chain | Residue |
| A | GLN101 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue IOD C 103 |
| Chain | Residue |
| C | TRP3 |
| C | IOD104 |
| C | PE3105 |
| C | PE3105 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue IOD C 104 |
| Chain | Residue |
| C | IOD103 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue PE3 C 105 |
| Chain | Residue |
| A | TRP97 |
| A | TRP97 |
| A | GLN101 |
| A | GOL204 |
| C | TRP1 |
| C | TRP1 |
| C | TRP3 |
| C | LYS6 |
| C | LYS6 |
| C | IOD103 |
| C | IOD103 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFrqpvDavklglpDYHkiIkqpMdmgtIkrrlenny..Ywaasecmqdfnt.MftNCyiY |
| Chain | Residue | Details |
| A | ALA96-TYR155 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 106 |
| Details | Domain: {"description":"Bromo 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37731000","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SB6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20048151","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2DVQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2DVS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
