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6U64

Mcl-1 bound to compound 17

Functional Information from GO Data
ChainGOidnamespacecontents
A0042981biological_processregulation of apoptotic process
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue Q0G A 401
ChainResidue
ALEU235
AQ0G403
AVAL249
AVAL253
APHE254
AARG263
ATHR266
ALEU267
APHE270
AQ0G402

site_idAC2
Number of Residues12
Detailsbinding site for residue Q0G A 402
ChainResidue
ATHR226
AALA227
AGLY230
AARG233
ALYS234
AASP256
AGLY257
AVAL258
AARG263
ATHR266
AQ0G401
AQ0G403

site_idAC3
Number of Residues6
Detailsbinding site for residue Q0G A 403
ChainResidue
AHIS224
AHIS224
ATHR226
AALA227
AQ0G401
AQ0G402

Functional Information from PROSITE/UniProt
site_idPS01080
Number of Residues20
DetailsBH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFsDGvtNWGRIVTLIsFGA
ChainResidueDetails
AVAL253-ALA272

site_idPS01258
Number of Residues12
DetailsBH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV
ChainResidueDetails
ATRP305-VAL316

site_idPS01259
Number of Residues15
DetailsBH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AletLRrVGDGVQRN
ChainResidueDetails
AALA209-ASN223

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
ChainResidueDetails
ALYS194
ALYS197

227561

PDB entries from 2024-11-20

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