6U2K
EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0002250 | biological_process | adaptive immune response |
| B | 0002376 | biological_process | immune system process |
| B | 0002468 | biological_process | dendritic cell antigen processing and presentation |
| B | 0002478 | biological_process | antigen processing and presentation of exogenous peptide antigen |
| B | 0005576 | cellular_component | extracellular region |
| B | 0022829 | molecular_function | wide pore channel activity |
| B | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| B | 0030670 | cellular_component | phagocytic vesicle membrane |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0042590 | biological_process | antigen processing and presentation of exogenous peptide antigen via MHC class I |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0045087 | biological_process | innate immune response |
| B | 0045335 | cellular_component | phagocytic vesicle |
| B | 0050829 | biological_process | defense response to Gram-negative bacterium |
| B | 0050830 | biological_process | defense response to Gram-positive bacterium |
| B | 0055085 | biological_process | transmembrane transport |
| B | 0061474 | cellular_component | phagolysosome membrane |
| B | 0140367 | biological_process | antibacterial innate immune response |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 29 |
| Details | Transmembrane: {"description":"Beta stranded","evidences":[{"source":"UniProtKB","id":"A1L314","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 315 |
| Details | Domain: {"description":"MACPF","evidences":[{"source":"PROSITE-ProRule","id":"PRU00745","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Site: {"description":"Cleavage; by LGMN","evidences":[{"source":"UniProtKB","id":"A1L314","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by trypsin","evidences":[{"source":"UniProtKB","id":"A1L314","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"31537793","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6U23","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6U2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6U2K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6U2L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6U2W","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
