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6U2K

EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex

Functional Information from GO Data
ChainGOidnamespacecontents
B0002250biological_processadaptive immune response
B0002376biological_processimmune system process
B0002468biological_processdendritic cell antigen processing and presentation
B0002478biological_processantigen processing and presentation of exogenous peptide antigen
B0002479biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
B0005576cellular_componentextracellular region
B0016020cellular_componentmembrane
B0022829molecular_functionwide pore channel activity
B0030659cellular_componentcytoplasmic vesicle membrane
B0030670cellular_componentphagocytic vesicle membrane
B0031410cellular_componentcytoplasmic vesicle
B0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
B0042742biological_processdefense response to bacterium
B0045087biological_processinnate immune response
B0045335cellular_componentphagocytic vesicle
B0050829biological_processdefense response to Gram-negative bacterium
B0050830biological_processdefense response to Gram-positive bacterium
B0055085biological_processtransmembrane transport
B0061474cellular_componentphagolysosome membrane
B0140367biological_processantibacterial innate immune response
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues29
DetailsTRANSMEM: Beta stranded => ECO:0000250|UniProtKB:A1L314
ChainResidueDetails
BTYR96-SER103
BGLY110-GLU115
BALA218-PHE227
BVAL231-TYR239

site_idSWS_FT_FI2
Number of Residues3
DetailsSITE: Cleavage; by LGMN => ECO:0000250|UniProtKB:A1L314
ChainResidueDetails
BASP335
BASN340
BASN342

site_idSWS_FT_FI3
Number of Residues1
DetailsSITE: Cleavage; by trypsin => ECO:0000250|UniProtKB:A1L314
ChainResidueDetails
BARG599

site_idSWS_FT_FI4
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:31537793, ECO:0007744|PDB:6U23, ECO:0007744|PDB:6U2J, ECO:0007744|PDB:6U2K, ECO:0007744|PDB:6U2L, ECO:0007744|PDB:6U2W
ChainResidueDetails
BASN168
BASN252

site_idSWS_FT_FI5
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
BASN358

237423

PDB entries from 2025-06-11

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