Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003743 | molecular_function | translation initiation factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006413 | biological_process | translational initiation |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003743 | molecular_function | translation initiation factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006413 | biological_process | translational initiation |
| C | 0003723 | molecular_function | RNA binding |
| C | 0003743 | molecular_function | translation initiation factor activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006413 | biological_process | translational initiation |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003743 | molecular_function | translation initiation factor activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006413 | biological_process | translational initiation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue EI8 A 301 |
| Chain | Residue |
| A | LEU60 |
| A | ARG157 |
| A | LYS162 |
| A | TRP166 |
| A | HOH427 |
| A | ASP90 |
| A | SER92 |
| A | PRO100 |
| A | MET101 |
| A | TRP102 |
| A | GLU103 |
| A | ARG112 |
| A | ASN155 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide EI8 B 301 and LYS B 162 |
| Chain | Residue |
| B | LEU60 |
| B | ASP90 |
| B | SER92 |
| B | PRO100 |
| B | MET101 |
| B | TRP102 |
| B | GLU103 |
| B | ARG112 |
| B | ILE115 |
| B | VAL154 |
| B | ASN155 |
| B | ARG157 |
| B | ASP161 |
| B | ILE163 |
| B | TRP166 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide EI8 C 301 and LYS C 162 |
| Chain | Residue |
| C | ASP90 |
| C | SER92 |
| C | PRO100 |
| C | MET101 |
| C | TRP102 |
| C | GLU103 |
| C | ARG112 |
| C | ILE115 |
| C | VAL154 |
| C | ASN155 |
| C | ARG157 |
| C | ASP161 |
| C | ILE163 |
| C | HOH406 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide EI8 D 301 and LYS D 162 |
| Chain | Residue |
| D | LEU60 |
| D | ASP90 |
| D | SER92 |
| D | PRO100 |
| D | MET101 |
| D | TRP102 |
| D | GLU103 |
| D | ARG112 |
| D | ILE115 |
| D | VAL154 |
| D | ASN155 |
| D | ARG157 |
| D | ASP161 |
| D | ILE163 |
Functional Information from PROSITE/UniProt
| site_id | PS00813 |
| Number of Residues | 24 |
| Details | IF4E Eukaryotic initiation factor 4E signature. DYslFKdgIePmWEDeknkrGGRW |
| Chain | Residue | Details |
| A | ASP90-TRP113 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 56 |
| Details | Region: {"description":"EIF4EBP1/2/3 binding","evidences":[{"source":"PubMed","id":"10394359","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10394359","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9200613","evidenceCode":"ECO:0000269"}]} |
