6TY5
Crystal structure of human TLR8 in complex with Compound 11
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002224 | biological_process | toll-like receptor signaling pathway |
| A | 0004888 | molecular_function | transmembrane signaling receptor activity |
| A | 0006955 | biological_process | immune response |
| A | 0016020 | cellular_component | membrane |
| B | 0002224 | biological_process | toll-like receptor signaling pathway |
| B | 0004888 | molecular_function | transmembrane signaling receptor activity |
| B | 0006955 | biological_process | immune response |
| B | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 1","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"LRR 2","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 4","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"LRR 5","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 6","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 7","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 44 |
| Details | Repeat: {"description":"LRR 8","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 44 |
| Details | Repeat: {"description":"LRR 9","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 10","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 11","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 13","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 14","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"LRR 15","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 44 |
| Details | Repeat: {"description":"LRR 16","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 19","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"LRR 20","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 21","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 23","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 20 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI20 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI21 |
| Number of Residues | 14 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI22 |
| Number of Residues | 21 |
| Details | Repeat: {"description":"LRR 18","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI23 |
| Number of Residues | 21 |
| Details | Repeat: {"description":"LRR 22","evidences":[{"source":"PubMed","id":"23520111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
