6TS0

Crystal structure of human L ferritin (HuLf) triple variant E60A-E61A-E64A Fe(III)-loaded for 30 minutes

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0005506	molecular_function	iron ion binding
AAA	0005515	molecular_function	protein binding
AAA	0005576	cellular_component	extracellular region
AAA	0005737	cellular_component	cytoplasm
AAA	0005829	cellular_component	cytosol
AAA	0006826	biological_process	iron ion transport
AAA	0006879	biological_process	intracellular iron ion homeostasis
AAA	0006880	biological_process	intracellular sequestering of iron ion
AAA	0008043	cellular_component	intracellular ferritin complex
AAA	0008198	molecular_function	ferrous iron binding
AAA	0008199	molecular_function	ferric iron binding
AAA	0016020	cellular_component	membrane
AAA	0035578	cellular_component	azurophil granule lumen
AAA	0042802	molecular_function	identical protein binding
AAA	0044754	cellular_component	autolysosome
AAA	0046872	molecular_function	metal ion binding
AAA	0055072	biological_process	obsolete iron ion homeostasis
AAA	0070062	cellular_component	extracellular exosome

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEthFLdeevklIK

Chain	Residue	Details
AAA	ASP126-LYS146

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING:

Chain	Residue	Details
AAA	GLU57
AAA	ALA60
AAA	ALA61
AAA	ALA64
AAA	GLU67

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylserine => ECO:0000269|PubMed:6653779

Chain	Residue	Details
AAA	SER5

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