Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0000307 | cellular_component | cyclin-dependent protein kinase holoenzyme complex |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
| B | 0016538 | molecular_function | cyclin-dependent protein serine/threonine kinase regulator activity |
| B | 0016592 | cellular_component | mediator complex |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0045023 | biological_process | G0 to G1 transition |
| B | 0045746 | biological_process | negative regulation of Notch signaling pathway |
| B | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| B | 1990508 | cellular_component | CKM complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue NZ8 A 501 |
| Chain | Residue |
| A | TYR32 |
| A | PHE97 |
| A | ASP98 |
| A | ALA100 |
| A | LEU142 |
| A | HIS149 |
| A | ILE171 |
| A | ALA172 |
| A | ASP173 |
| A | MET174 |
| A | PHE176 |
| A | VAL35 |
| A | ARG356 |
| A | ALA50 |
| A | LYS52 |
| A | GLU66 |
| A | LEU70 |
| A | LEU73 |
| A | VAL78 |
| A | ILE79 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue FMT A 502 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 503 |
| Chain | Residue |
| A | LEU148 |
| A | ARG150 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue FMT A 504 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue NZ5 A 505 |
| Chain | Residue |
| A | GLN82 |
| A | FMT504 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue NZ5 A 506 |
| Chain | Residue |
| A | PRO341 |
| A | SER343 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue NZ5 A 507 |
| Chain | Residue |
| A | ARG125 |
| A | ALA308 |
| A | TYR334 |
| A | GLU337 |
| A | HOH645 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue FMT B 301 |
| Chain | Residue |
| B | LYS226 |
| B | GLU229 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue FMT B 302 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue FMT B 303 |
| Chain | Residue |
| B | ASP187 |
| B | LEU191 |
| B | VAL233 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue FMT B 304 |
| Chain | Residue |
| B | ASN46 |
| B | ASP182 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue FMT B 305 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue FMT B 306 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue FMT B 307 |
| Chain | Residue |
| B | ILE15 |
| B | HOH411 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 308 |
| Chain | Residue |
| A | LYS307 |
| A | LEU336 |
| A | GLU337 |
| B | HOH410 |
| site_id | AD7 |
| Number of Residues | 1 |
| Details | binding site for residue FMT B 309 |
| site_id | AD8 |
| Number of Residues | 1 |
| Details | binding site for residue NZ5 B 310 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 26 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGRGTYGHVYkAkrkdgkddkd........YALK |
| Chain | Residue | Details |
| A | VAL27-LYS52 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VlHrDLKpaNILV |
| Chain | Residue | Details |
| A | VAL147-VAL159 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | SER275 | |
| Chain | Residue | Details |
| A | VAL27 | |
| A | LYS52 | |
