6TMG
Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase dimer, membrane region model
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| a | 0000276 | cellular_component | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) |
| a | 0015078 | molecular_function | proton transmembrane transporter activity |
| a | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| A | 0000276 | cellular_component | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) |
| A | 0015078 | molecular_function | proton transmembrane transporter activity |
| A | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| c | 0005743 | cellular_component | mitochondrial inner membrane |
| c | 0005750 | cellular_component | mitochondrial respiratory chain complex III |
| c | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| c | 0009055 | molecular_function | electron transfer activity |
| c | 0020037 | molecular_function | heme binding |
| c | 0046872 | molecular_function | metal ion binding |
| C | 0005743 | cellular_component | mitochondrial inner membrane |
| C | 0005750 | cellular_component | mitochondrial respiratory chain complex III |
| C | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| C | 0009055 | molecular_function | electron transfer activity |
| C | 0020037 | molecular_function | heme binding |
| C | 0046872 | molecular_function | metal ion binding |
| j | 0016020 | cellular_component | membrane |
| J | 0016020 | cellular_component | membrane |
| k | 0016020 | cellular_component | membrane |
| K | 0016020 | cellular_component | membrane |
| u | 0016020 | cellular_component | membrane |
| U | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue PC1 o 201 |
| Chain | Residue |
| a | LEU215 |
| o | SER39 |
| o | GLN40 |
| o | THR43 |
| o | CDL203 |
| w | LEU91 |
| w | THR95 |
| w | ARG96 |
| w | PRO99 |
| a | ALA217 |
| a | MET219 |
| d | TYR62 |
| h | CDL302 |
| j | PHE105 |
| j | PEE301 |
| j | PEE302 |
| o | SER35 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue LMT o 202 |
| Chain | Residue |
| o | PHE60 |
| o | THR64 |
| o | ASP99 |
| o | ASP100 |
| x | TRP30 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue CDL o 203 |
| Chain | Residue |
| c | PRO74 |
| c | CDL404 |
| d | TYR71 |
| d | PHE75 |
| f | TYR248 |
| h | CDL302 |
| j | PHE90 |
| j | PEE302 |
| o | PHE24 |
| o | ARG28 |
| o | ARG31 |
| o | LEU32 |
| o | SER35 |
| o | VAL48 |
| o | PC1201 |
| o | PC1204 |
| w | THR95 |
| w | ARG96 |
| x | TRP25 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue PC1 o 204 |
| Chain | Residue |
| d | MET79 |
| d | TYR82 |
| d | PHE87 |
| f | PRO243 |
| f | SER247 |
| h | CDL302 |
| j | PEE302 |
| o | ARG15 |
| o | VAL17 |
| o | GLY20 |
| o | MET21 |
| o | CDL203 |
| s | PHE58 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue PEE j 301 |
| Chain | Residue |
| d | LMT403 |
| h | TYR230 |
| h | CDL302 |
| j | PHE105 |
| j | TRP108 |
| j | SER109 |
| j | ARG110 |
| j | PEE302 |
| k | THR160 |
| k | PHE220 |
| o | PC1201 |
| w | PHE85 |
| w | VAL86 |
| w | MET88 |
| x | THR13 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | binding site for residue PEE j 302 |
| Chain | Residue |
| c | LMT403 |
| c | CDL404 |
| h | CDL302 |
| j | TRP80 |
| j | PHE89 |
| j | PHE104 |
| j | TRP107 |
| j | TRP108 |
| j | SER109 |
| j | ASP113 |
| j | PEE301 |
| o | PC1201 |
| o | CDL203 |
| o | PC1204 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue CDL u 201 |
| Chain | Residue |
| c | PHE139 |
| c | PHE144 |
| c | ARG147 |
| c | LMT401 |
| c | PEE402 |
| c | LMT403 |
| e | TRP196 |
| h | LMT301 |
| s | PHE62 |
| s | TRP63 |
| u | TYR57 |
| u | TYR60 |
| u | ARG64 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue LMT h 301 |
| Chain | Residue |
| h | ALA224 |
| h | ARG225 |
| s | GLN65 |
| s | THR69 |
| u | MET63 |
| u | CDL201 |
| x | LMT101 |
| c | LMT403 |
| h | ARG222 |
| h | ARG223 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | binding site for residue CDL h 302 |
| Chain | Residue |
| c | LMT403 |
| h | ARG225 |
| h | LYS228 |
| h | ILE231 |
| j | TRP108 |
| j | ARG110 |
| j | PEE301 |
| j | PEE302 |
| o | PHE24 |
| o | PC1201 |
| o | CDL203 |
| o | PC1204 |
| s | SER60 |
| s | PRO61 |
| x | TRP25 |
| x | ASN28 |
| x | LMT101 |
| site_id | AD1 |
| Number of Residues | 19 |
| Details | binding site for residue CDL e 401 |
| Chain | Residue |
| B | CDL601 |
| b | CYS254 |
| b | LEU256 |
| b | GLY257 |
| b | VAL258 |
| b | PHE260 |
| c | PEE402 |
| e | PHE186 |
| e | SER189 |
| e | LEU190 |
| n | GLU158 |
| n | SER159 |
| n | LEU160 |
| v | ILE9 |
| v | ILE16 |
| v | ILE82 |
| v | ARG86 |
| v | LYS90 |
| v | CDL201 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue LMT x 101 |
| Chain | Residue |
| h | ARG222 |
| h | ARG223 |
| h | LMT301 |
| h | CDL302 |
| s | GLN65 |
| s | LYS68 |
| x | ASN28 |
| x | GLU32 |
| x | SER53 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue CDL b 601 |
| Chain | Residue |
| K | LEU193 |
| K | PHE196 |
| b | ASN246 |
| b | LEU247 |
| b | VAL248 |
| b | SER249 |
| v | ASN17 |
| site_id | AD4 |
| Number of Residues | 13 |
| Details | binding site for residue CDL v 201 |
| Chain | Residue |
| d | CDL402 |
| e | ARG181 |
| e | THR182 |
| e | TYR183 |
| e | LEU184 |
| e | PRO185 |
| e | PHE186 |
| e | CDL401 |
| v | TRP79 |
| v | TYR83 |
| v | MET84 |
| v | LYS87 |
| w | PRO72 |
| site_id | AD5 |
| Number of Residues | 10 |
| Details | binding site for residue PC1 v 202 |
| Chain | Residue |
| b | TRP271 |
| b | THR276 |
| d | THR272 |
| d | CDL402 |
| e | SER179 |
| k | SER212 |
| v | TYR73 |
| v | TYR76 |
| v | LYS77 |
| v | HIS80 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue LMT c 401 |
| Chain | Residue |
| c | PHE144 |
| c | TYR145 |
| c | ARG147 |
| c | LMT403 |
| j | PRO115 |
| j | PRO116 |
| j | LYS117 |
| u | CDL201 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue PEE c 402 |
| Chain | Residue |
| c | TYR143 |
| c | ARG147 |
| d | PHE123 |
| e | TRP187 |
| e | CDL401 |
| u | TYR57 |
| u | CDL201 |
| site_id | AD8 |
| Number of Residues | 10 |
| Details | binding site for residue LMT c 403 |
| Chain | Residue |
| c | TYR145 |
| c | LMT401 |
| c | CDL404 |
| h | ARG225 |
| h | LMT301 |
| h | CDL302 |
| j | PEE302 |
| s | PHE58 |
| s | GLN65 |
| u | CDL201 |
| site_id | AD9 |
| Number of Residues | 15 |
| Details | binding site for residue CDL c 404 |
| Chain | Residue |
| c | PHE122 |
| c | GLN125 |
| c | SER126 |
| c | VAL129 |
| c | TYR130 |
| c | LMT403 |
| d | LYS95 |
| j | PRO74 |
| j | VAL75 |
| j | TRP76 |
| j | PHE90 |
| j | PHE104 |
| j | PEE302 |
| o | CDL203 |
| w | PHE69 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue LMT d 401 |
| Chain | Residue |
| d | LEU269 |
| d | SER277 |
| d | ASN291 |
| k | GLU176 |
| site_id | AE2 |
| Number of Residues | 11 |
| Details | binding site for residue CDL d 402 |
| Chain | Residue |
| d | GLY270 |
| d | PHE271 |
| d | THR272 |
| e | SER179 |
| e | ARG181 |
| m | TYR134 |
| m | SER137 |
| m | ILE138 |
| v | TYR76 |
| v | CDL201 |
| v | PC1202 |
| site_id | AE3 |
| Number of Residues | 8 |
| Details | binding site for residue LMT d 403 |
| Chain | Residue |
| d | ASP259 |
| d | TYR264 |
| j | ARG122 |
| j | PEE301 |
| m | ASN120 |
| m | ALA121 |
| m | TYR124 |
| m | CYS125 |
| site_id | AE4 |
| Number of Residues | 13 |
| Details | binding site for residue PC1 O 201 |
| Chain | Residue |
| A | LEU215 |
| H | CDL302 |
| J | PHE105 |
| J | PEE301 |
| J | PEE302 |
| O | SER35 |
| O | SER39 |
| O | GLN40 |
| O | THR43 |
| O | CDL203 |
| W | LEU91 |
| W | THR95 |
| W | ARG96 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue LMT O 202 |
| Chain | Residue |
| O | PHE60 |
| O | THR64 |
| O | ASP99 |
| O | ASP100 |
| X | TRP30 |
| site_id | AE6 |
| Number of Residues | 16 |
| Details | binding site for residue CDL O 203 |
| Chain | Residue |
| C | PRO74 |
| C | CDL404 |
| D | TYR71 |
| D | PHE75 |
| F | TYR248 |
| H | CDL302 |
| J | PEE302 |
| O | PHE24 |
| O | ARG28 |
| O | ARG31 |
| O | LEU32 |
| O | SER35 |
| O | PC1201 |
| O | PC1204 |
| W | ARG96 |
| X | TRP25 |
| site_id | AE7 |
| Number of Residues | 18 |
| Details | binding site for residue PEE J 301 |
| Chain | Residue |
| D | LMT403 |
| H | ARG225 |
| H | TYR230 |
| H | CDL302 |
| J | PHE102 |
| J | PHE105 |
| J | TRP108 |
| J | SER109 |
| J | ARG110 |
| J | PEE302 |
| K | THR160 |
| K | PHE220 |
| O | PC1201 |
| W | PHE85 |
| W | VAL86 |
| W | PHE87 |
| W | MET88 |
| X | THR13 |
| site_id | AE8 |
| Number of Residues | 15 |
| Details | binding site for residue PEE J 302 |
| Chain | Residue |
| C | LMT403 |
| C | CDL404 |
| D | PHE87 |
| H | ARG225 |
| H | CDL302 |
| J | PHE104 |
| J | TRP107 |
| J | TRP108 |
| J | SER109 |
| J | ASP113 |
| J | PEE301 |
| O | PC1201 |
| O | CDL203 |
| O | PC1204 |
| X | TRP25 |
| site_id | AE9 |
| Number of Residues | 16 |
| Details | binding site for residue CDL U 201 |
| Chain | Residue |
| C | PHE139 |
| C | PHE144 |
| C | ARG147 |
| C | LMT401 |
| C | PEE402 |
| C | LMT403 |
| D | PHE123 |
| E | TRP196 |
| H | LMT301 |
| S | PHE62 |
| S | TRP63 |
| U | ALA53 |
| U | TYR57 |
| U | TYR60 |
| U | ARG61 |
| U | ARG64 |
| site_id | AF1 |
| Number of Residues | 12 |
| Details | binding site for residue LMT H 301 |
| Chain | Residue |
| C | LMT403 |
| H | ARG222 |
| H | ARG223 |
| H | ALA224 |
| H | ARG225 |
| S | GLN65 |
| S | THR69 |
| U | TYR60 |
| U | MET63 |
| U | GLU71 |
| U | CDL201 |
| X | LMT101 |
| site_id | AF2 |
| Number of Residues | 16 |
| Details | binding site for residue CDL H 302 |
| Chain | Residue |
| C | LMT403 |
| H | ARG225 |
| H | LYS228 |
| H | ILE231 |
| J | TRP108 |
| J | ARG110 |
| J | PEE301 |
| J | PEE302 |
| O | PHE24 |
| O | PC1201 |
| O | CDL203 |
| O | PC1204 |
| S | PRO61 |
| S | GLN65 |
| X | ASN28 |
| X | LMT101 |
| site_id | AF3 |
| Number of Residues | 20 |
| Details | binding site for residue CDL E 401 |
| Chain | Residue |
| B | CYS254 |
| B | LEU256 |
| B | GLY257 |
| B | VAL258 |
| B | PHE260 |
| C | PEE402 |
| E | PHE186 |
| E | SER189 |
| E | LEU190 |
| N | GLU158 |
| N | SER159 |
| N | LEU160 |
| V | ILE9 |
| V | THR75 |
| V | ALA78 |
| V | ILE82 |
| V | ARG86 |
| V | LYS90 |
| V | CDL201 |
| V | CDL202 |
| site_id | AF4 |
| Number of Residues | 9 |
| Details | binding site for residue LMT X 101 |
| Chain | Residue |
| H | ARG222 |
| H | ARG223 |
| H | LMT301 |
| H | CDL302 |
| S | GLN65 |
| S | LYS68 |
| X | ASN28 |
| X | GLU32 |
| X | SER53 |
| site_id | AF5 |
| Number of Residues | 24 |
| Details | binding site for residue CDL B 601 |
| Chain | Residue |
| B | TYR99 |
| B | LYS101 |
| B | PHE272 |
| B | THR276 |
| B | PHE277 |
| B | GLY280 |
| B | ALA281 |
| B | TYR284 |
| V | TRP61 |
| V | TRP62 |
| V | GLN63 |
| V | LEU70 |
| V | TYR73 |
| V | CDL201 |
| b | ARG103 |
| b | CYS254 |
| b | LEU262 |
| e | CDL401 |
| v | HIS4 |
| v | PHE5 |
| v | GLN6 |
| v | TRP61 |
| v | GLY74 |
| v | MET81 |
| site_id | AF6 |
| Number of Residues | 11 |
| Details | binding site for residue CDL B 602 |
| Chain | Residue |
| B | ASN246 |
| B | LEU247 |
| B | VAL248 |
| B | SER249 |
| V | ASN17 |
| V | THR22 |
| V | ARG23 |
| k | PHE190 |
| k | PHE192 |
| k | LEU193 |
| k | PHE196 |
| site_id | AF7 |
| Number of Residues | 23 |
| Details | binding site for residue CDL V 201 |
| Chain | Residue |
| B | ARG103 |
| B | CYS254 |
| B | LEU262 |
| B | CDL601 |
| E | CDL401 |
| V | HIS4 |
| V | PHE5 |
| V | GLN6 |
| V | TRP61 |
| V | VAL71 |
| V | GLY74 |
| V | THR75 |
| V | LYS77 |
| V | MET81 |
| b | TYR99 |
| b | LYS101 |
| b | PHE272 |
| b | THR276 |
| b | ALA281 |
| b | TYR284 |
| v | TRP62 |
| v | LEU70 |
| v | TYR73 |
| site_id | AF8 |
| Number of Residues | 14 |
| Details | binding site for residue CDL V 202 |
| Chain | Residue |
| D | CDL402 |
| E | ARG181 |
| E | THR182 |
| E | TYR183 |
| E | LEU184 |
| E | PRO185 |
| E | PHE186 |
| E | CDL401 |
| M | MET140 |
| V | TRP79 |
| V | TYR83 |
| V | MET84 |
| V | LYS87 |
| W | PRO72 |
| site_id | AF9 |
| Number of Residues | 11 |
| Details | binding site for residue PC1 V 203 |
| Chain | Residue |
| B | TRP271 |
| B | THR276 |
| D | THR272 |
| D | CDL402 |
| E | SER179 |
| K | SER212 |
| V | TYR73 |
| V | TYR76 |
| V | LYS77 |
| V | HIS80 |
| W | PHE85 |
| site_id | AG1 |
| Number of Residues | 9 |
| Details | binding site for residue LMT C 401 |
| Chain | Residue |
| C | PHE144 |
| C | TYR145 |
| C | ARG147 |
| C | LMT403 |
| J | PRO115 |
| J | PRO116 |
| J | LYS117 |
| J | LEU120 |
| U | CDL201 |
| site_id | AG2 |
| Number of Residues | 7 |
| Details | binding site for residue PEE C 402 |
| Chain | Residue |
| C | TYR143 |
| C | ARG147 |
| D | PHE123 |
| E | TRP187 |
| E | CDL401 |
| U | TYR57 |
| U | CDL201 |
| site_id | AG3 |
| Number of Residues | 9 |
| Details | binding site for residue LMT C 403 |
| Chain | Residue |
| C | TYR145 |
| C | LMT401 |
| C | CDL404 |
| H | ARG225 |
| H | LMT301 |
| H | CDL302 |
| J | PEE302 |
| S | GLN65 |
| U | CDL201 |
| site_id | AG4 |
| Number of Residues | 15 |
| Details | binding site for residue CDL C 404 |
| Chain | Residue |
| C | PHE122 |
| C | GLN125 |
| C | SER126 |
| C | VAL129 |
| C | TYR130 |
| C | LMT403 |
| D | LYS95 |
| J | PRO74 |
| J | VAL75 |
| J | TRP76 |
| J | PHE90 |
| J | PHE104 |
| J | PEE302 |
| O | CDL203 |
| W | PHE69 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue LMT D 401 |
| Chain | Residue |
| D | LEU269 |
| D | SER277 |
| D | ASN291 |
| K | GLU176 |
| site_id | AG6 |
| Number of Residues | 11 |
| Details | binding site for residue CDL D 402 |
| Chain | Residue |
| D | GLY270 |
| D | PHE271 |
| D | THR272 |
| E | SER179 |
| E | ARG181 |
| M | TYR134 |
| M | SER137 |
| M | ILE138 |
| M | LEU148 |
| V | CDL202 |
| V | PC1203 |
| site_id | AG7 |
| Number of Residues | 7 |
| Details | binding site for residue LMT D 403 |
| Chain | Residue |
| D | TYR264 |
| J | ARG122 |
| J | PEE301 |
| M | ASN120 |
| M | ALA121 |
| M | TYR124 |
| M | CYS125 |
| site_id | AG8 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide PC1 O 204 and ARG O 15 |
| Chain | Residue |
| D | TYR82 |
| D | PHE87 |
| H | CDL302 |
| J | PEE302 |
| O | VAL12 |
| O | LYS13 |
| O | GLY14 |
| O | SER16 |
| O | VAL17 |
| O | ALA19 |
| O | GLY20 |
| O | MET21 |
| O | SER23 |
| O | CDL203 |
| S | ASP40 |
| S | SER41 |
| S | TRP45 |
| S | PHE58 |
