Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005200 | molecular_function | structural constituent of cytoskeleton |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005874 | cellular_component | microtubule |
| A | 0007017 | biological_process | microtubule-based process |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005200 | molecular_function | structural constituent of cytoskeleton |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005874 | cellular_component | microtubule |
| B | 0007017 | biological_process | microtubule-based process |
| C | 0005200 | molecular_function | structural constituent of cytoskeleton |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005874 | cellular_component | microtubule |
| C | 0007017 | biological_process | microtubule-based process |
| D | 0003924 | molecular_function | GTPase activity |
| D | 0005200 | molecular_function | structural constituent of cytoskeleton |
| D | 0005525 | molecular_function | GTP binding |
| D | 0005874 | cellular_component | microtubule |
| D | 0007017 | biological_process | microtubule-based process |
| E | 0031110 | biological_process | regulation of microtubule polymerization or depolymerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | PRO175 |
| A | LYS394 |
| B | ASN349 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | binding site for residue GTP A 502 |
| Chain | Residue |
| A | ASN101 |
| A | SER140 |
| A | GLY143 |
| A | GLY144 |
| A | THR145 |
| A | GLY146 |
| A | VAL177 |
| A | SER178 |
| A | GLU183 |
| A | ASN206 |
| A | TYR224 |
| A | ASN228 |
| A | ILE231 |
| A | MG503 |
| A | HOH602 |
| A | HOH605 |
| A | HOH607 |
| A | HOH608 |
| A | HOH609 |
| A | HOH616 |
| B | LYS254 |
| A | GLY10 |
| A | GLN11 |
| A | ALA12 |
| A | GLN15 |
| A | ASP98 |
| A | ALA99 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 503 |
| Chain | Residue |
| A | GTP502 |
| A | HOH602 |
| A | HOH605 |
| A | HOH607 |
| A | HOH608 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 501 |
| Chain | Residue |
| B | LEU219 |
| B | THR220 |
| B | THR221 |
| C | LYS326 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| B | THR223 |
| B | GLY225 |
| B | ARG278 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | binding site for residue GDP B 503 |
| Chain | Residue |
| B | GLY10 |
| B | GLN11 |
| B | CYS12 |
| B | GLN15 |
| B | SER140 |
| B | GLY143 |
| B | GLY144 |
| B | THR145 |
| B | GLY146 |
| B | PRO173 |
| B | VAL177 |
| B | ASP179 |
| B | GLU183 |
| B | ASN206 |
| B | TYR224 |
| B | ASN228 |
| B | HOH602 |
| B | HOH605 |
| B | HOH606 |
| B | HOH609 |
| B | HOH612 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | binding site for residue N9B B 504 |
| Chain | Residue |
| A | ALA180 |
| A | VAL181 |
| B | VAL238 |
| B | CYS241 |
| B | LEU242 |
| B | LEU248 |
| B | ASN249 |
| B | ALA250 |
| B | ASN258 |
| B | MET259 |
| B | VAL315 |
| B | ALA316 |
| B | ASN350 |
| B | LYS352 |
| B | ILE378 |
| B | HOH611 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 501 |
| Chain | Residue |
| C | ARG215 |
| C | LYS304 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 502 |
| Chain | Residue |
| C | ARG390 |
| C | LYS394 |
| site_id | AD1 |
| Number of Residues | 28 |
| Details | binding site for residue GTP C 503 |
| Chain | Residue |
| C | ASN206 |
| C | TYR224 |
| C | ASN228 |
| C | ILE231 |
| C | HOH606 |
| C | HOH608 |
| C | HOH611 |
| C | HOH612 |
| C | HOH614 |
| C | HOH617 |
| D | LYS254 |
| D | MG501 |
| C | GLY10 |
| C | GLN11 |
| C | ALA12 |
| C | GLN15 |
| C | ASP98 |
| C | ALA99 |
| C | ASN101 |
| C | SER140 |
| C | GLY143 |
| C | GLY144 |
| C | THR145 |
| C | GLY146 |
| C | ILE171 |
| C | VAL177 |
| C | SER178 |
| C | GLU183 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 501 |
| Chain | Residue |
| C | GTP503 |
| C | HOH611 |
| C | HOH614 |
| D | LYS254 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 502 |
| Chain | Residue |
| D | THR223 |
| D | ARG278 |
| D | PHE404 |
| D | HIS406 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 503 |
| Chain | Residue |
| D | LYS19 |
| D | HIS229 |
| D | ARG278 |
| site_id | AD5 |
| Number of Residues | 24 |
| Details | binding site for residue GDP D 504 |
| Chain | Residue |
| D | GLY10 |
| D | GLN11 |
| D | CYS12 |
| D | GLN15 |
| D | SER140 |
| D | GLY143 |
| D | GLY144 |
| D | THR145 |
| D | GLY146 |
| D | PRO173 |
| D | VAL177 |
| D | SER178 |
| D | ASP179 |
| D | GLU183 |
| D | ASN206 |
| D | TYR224 |
| D | ASN228 |
| D | HOH604 |
| D | HOH605 |
| D | HOH607 |
| D | HOH610 |
| D | HOH614 |
| D | HOH619 |
| D | HOH624 |
| site_id | AD6 |
| Number of Residues | 16 |
| Details | binding site for residue N9B D 505 |
| Chain | Residue |
| C | ASN101 |
| C | ALA180 |
| C | VAL181 |
| D | CYS241 |
| D | LEU242 |
| D | LEU248 |
| D | ALA250 |
| D | ASP251 |
| D | LEU255 |
| D | ASN258 |
| D | MET259 |
| D | VAL315 |
| D | ALA316 |
| D | ASN350 |
| D | LYS352 |
| D | ILE378 |
Functional Information from PROSITE/UniProt
| site_id | PS00227 |
| Number of Residues | 7 |
| Details | TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG |
| Chain | Residue | Details |
| A | GLY142-GLY148 | |
| B | GLY142-GLY148 | |
| site_id | PS00228 |
| Number of Residues | 4 |
| Details | TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI |
| Chain | Residue | Details |
| B | MET1-ILE4 | |
| site_id | PS00563 |
| Number of Residues | 10 |
| Details | STATHMIN_1 Stathmin family signature 1. PRRRDpSLEE |
| Chain | Residue | Details |
| E | PRO40-GLU49 | |
| site_id | PS01041 |
| Number of Residues | 10 |
| Details | STATHMIN_2 Stathmin family signature 2. AEKREHEREV |
| Chain | Residue | Details |
| E | ALA73-VAL82 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]} |
