6T4K

ROR(gamma)t ligand binding domain in complex with desmosterol and allosteric ligand MRL871

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MHQ A 601

Chain	Residue
A	GLN286
A	MET365
A	HIS479
A	GOL603
A	HOH725

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site_id	AC2
Number of Residues	17
Details	binding site for residue 4F1 A 602

Chain	Residue
A	GLN329
A	LEU353
A	LYS354
A	MET358
A	LEU483
A	GLN484
A	GLN487
A	ALA496
A	ALA497
A	PHE498
A	TYR502
A	LEU505
A	PHE506
A	ALA321
A	LEU324
A	THR325
A	ILE328

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site_id	AC3
Number of Residues	6
Details	binding site for residue GOL A 603

Chain	Residue
A	HIS323
A	PHE377
A	PHE378
A	GLU379
A	MHQ601
A	HOH706

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site_id	AC4
Number of Residues	7
Details	binding site for residue GOL A 604

Chain	Residue
A	ARG282
A	GLU283
A	THR284
A	CYS285
A	GLN286
A	TYR330
A	HOH712

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