6T4B

CRYSTAL STRUCTURE OF HUMAN TDP-43 N-TERMINAL DOMAIN AT 2.55 A RESOLUTION

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SO4 A 101

Chain	Residue
A	TYR43
A	ARG52
A	PRO64
A	ASP65
A	HOH202
I	SER2
I	PRO19

---

site_id	AC2
Number of Residues	9
Details	binding site for residue SO4 C 101

Chain	Residue
C	TYR43
C	ARG52
C	ARG55
C	PRO64
C	ASP65
C	HOH202
C	HOH213
A	SER2
A	PRO19

---

site_id	AC3
Number of Residues	8
Details	binding site for residue SO4 E 101

Chain	Residue
C	SER2
C	PRO19
E	TYR43
E	ARG52
E	ARG55
E	PRO64
E	ASP65
E	HOH206

---

site_id	AC4
Number of Residues	8
Details	binding site for residue SO4 G 101

Chain	Residue
E	PRO19
G	TYR43
G	ARG52
G	ARG55
G	PRO64
G	ASP65
G	HOH209
G	HOH214

---

site_id	AC5
Number of Residues	6
Details	binding site for residue SO4 I 101

Chain	Residue
G	GLU3
I	TYR43
I	ARG52
I	ARG55
I	PRO64
I	ASP65

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---