6T3E
Structure of Thermococcus litoralis Delta(1)-pyrroline-2-carboxylate reductase in complex with NADH and L-proline
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000286 | molecular_function | alanine dehydrogenase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000286 | molecular_function | alanine dehydrogenase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006522 | biological_process | alanine metabolic process |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue PRO A 401 |
| Chain | Residue |
| A | ARG43 |
| A | LYS71 |
| A | VAL73 |
| A | THR111 |
| A | ARG114 |
| A | TRP227 |
| A | VAL301 |
| A | GLY302 |
| A | NAI402 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue NAI A 402 |
| Chain | Residue |
| A | LEU75 |
| A | SER86 |
| A | ARG114 |
| A | THR115 |
| A | GLY140 |
| A | VAL141 |
| A | GLN142 |
| A | ASP163 |
| A | ILE164 |
| A | ASN168 |
| A | ALA203 |
| A | THR204 |
| A | THR205 |
| A | ALA206 |
| A | VAL225 |
| A | GLY226 |
| A | TRP227 |
| A | SER300 |
| A | VAL301 |
| A | GLY302 |
| A | PRO401 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue PRO B 401 |
| Chain | Residue |
| B | ARG43 |
| B | MET58 |
| B | LYS71 |
| B | VAL73 |
| B | THR111 |
| B | ARG114 |
| B | TRP227 |
| B | VAL301 |
| B | NAI402 |
| site_id | AC4 |
| Number of Residues | 25 |
| Details | binding site for residue NAI B 402 |
| Chain | Residue |
| B | LEU75 |
| B | SER86 |
| B | ARG114 |
| B | THR115 |
| B | GLY140 |
| B | VAL141 |
| B | GLN142 |
| B | ASP163 |
| B | ILE164 |
| B | ASN168 |
| B | ALA203 |
| B | THR204 |
| B | THR205 |
| B | ALA206 |
| B | VAL210 |
| B | VAL225 |
| B | GLY226 |
| B | TRP227 |
| B | SER300 |
| B | VAL301 |
| B | GLY302 |
| B | PRO401 |
| B | HOH502 |
| B | HOH503 |
| B | HOH505 |
