6SWD
IC2 body model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| 0 | 0005840 | cellular_component | ribosome |
| 0 | 1990904 | cellular_component | ribonucleoprotein complex |
| 6 | 0003723 | molecular_function | RNA binding |
| 6 | 0003743 | molecular_function | translation initiation factor activity |
| 6 | 0006412 | biological_process | translation |
| 6 | 0006413 | biological_process | translational initiation |
| A | 0003735 | molecular_function | structural constituent of ribosome |
| A | 0005840 | cellular_component | ribosome |
| A | 0006412 | biological_process | translation |
| A | 1990904 | cellular_component | ribonucleoprotein complex |
| B | 0003735 | molecular_function | structural constituent of ribosome |
| B | 0005840 | cellular_component | ribosome |
| B | 0006412 | biological_process | translation |
| B | 0015935 | cellular_component | small ribosomal subunit |
| B | 1990904 | cellular_component | ribonucleoprotein complex |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003735 | molecular_function | structural constituent of ribosome |
| D | 0005840 | cellular_component | ribosome |
| D | 0006412 | biological_process | translation |
| D | 0015935 | cellular_component | small ribosomal subunit |
| D | 0019843 | molecular_function | rRNA binding |
| D | 0042274 | biological_process | ribosomal small subunit biogenesis |
| D | 0043226 | cellular_component | organelle |
| D | 1990904 | cellular_component | ribonucleoprotein complex |
| E | 0003723 | molecular_function | RNA binding |
| E | 0003735 | molecular_function | structural constituent of ribosome |
| E | 0005840 | cellular_component | ribosome |
| E | 0006412 | biological_process | translation |
| E | 0019843 | molecular_function | rRNA binding |
| E | 0022627 | cellular_component | cytosolic small ribosomal subunit |
| E | 1990904 | cellular_component | ribonucleoprotein complex |
| F | 0003723 | molecular_function | RNA binding |
| F | 0003735 | molecular_function | structural constituent of ribosome |
| F | 0005840 | cellular_component | ribosome |
| F | 0006412 | biological_process | translation |
| F | 0015935 | cellular_component | small ribosomal subunit |
| F | 0019843 | molecular_function | rRNA binding |
| F | 0022627 | cellular_component | cytosolic small ribosomal subunit |
| F | 1990904 | cellular_component | ribonucleoprotein complex |
| G | 0003735 | molecular_function | structural constituent of ribosome |
| G | 0005840 | cellular_component | ribosome |
| G | 0006412 | biological_process | translation |
| G | 1990904 | cellular_component | ribonucleoprotein complex |
| I | 0003723 | molecular_function | RNA binding |
| I | 0003735 | molecular_function | structural constituent of ribosome |
| I | 0005840 | cellular_component | ribosome |
| I | 0006412 | biological_process | translation |
| I | 0019843 | molecular_function | rRNA binding |
| I | 1990904 | cellular_component | ribonucleoprotein complex |
| J | 0003735 | molecular_function | structural constituent of ribosome |
| J | 0005840 | cellular_component | ribosome |
| J | 0006412 | biological_process | translation |
| J | 1990904 | cellular_component | ribonucleoprotein complex |
| M | 0003723 | molecular_function | RNA binding |
| M | 0003735 | molecular_function | structural constituent of ribosome |
| M | 0005840 | cellular_component | ribosome |
| M | 0006412 | biological_process | translation |
| M | 0019843 | molecular_function | rRNA binding |
| M | 1990904 | cellular_component | ribonucleoprotein complex |
| N | 0003723 | molecular_function | RNA binding |
| N | 0003735 | molecular_function | structural constituent of ribosome |
| N | 0005840 | cellular_component | ribosome |
| N | 0006412 | biological_process | translation |
| N | 0015935 | cellular_component | small ribosomal subunit |
| N | 0019843 | molecular_function | rRNA binding |
| N | 1990904 | cellular_component | ribonucleoprotein complex |
| Q | 0003735 | molecular_function | structural constituent of ribosome |
| Q | 0005840 | cellular_component | ribosome |
| Q | 0006412 | biological_process | translation |
| Q | 0022627 | cellular_component | cytosolic small ribosomal subunit |
| Q | 0070181 | molecular_function | small ribosomal subunit rRNA binding |
| Q | 1990904 | cellular_component | ribonucleoprotein complex |
| R | 0003723 | molecular_function | RNA binding |
| R | 0003735 | molecular_function | structural constituent of ribosome |
| R | 0005840 | cellular_component | ribosome |
| R | 0006412 | biological_process | translation |
| R | 0019843 | molecular_function | rRNA binding |
| R | 0022627 | cellular_component | cytosolic small ribosomal subunit |
| R | 1990904 | cellular_component | ribonucleoprotein complex |
| V | 0003735 | molecular_function | structural constituent of ribosome |
| V | 0005840 | cellular_component | ribosome |
| V | 0006412 | biological_process | translation |
| V | 1990904 | cellular_component | ribonucleoprotein complex |
| W | 0003735 | molecular_function | structural constituent of ribosome |
| W | 0005840 | cellular_component | ribosome |
| W | 0006412 | biological_process | translation |
| W | 0008270 | molecular_function | zinc ion binding |
| W | 0046872 | molecular_function | metal ion binding |
| W | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue MG 2 1601 |
| Chain | Residue |
| 2 | G28 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue MG 2 1602 |
| Chain | Residue |
| 2 | A539 |
| 2 | A540 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue MG 2 1603 |
| Chain | Residue |
| 2 | C39 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue MG 2 1604 |
| Chain | Residue |
| 2 | A1370 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue MG 2 1605 |
| Chain | Residue |
| 2 | A574 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue MG 2 1606 |
| Chain | Residue |
| 2 | A587 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue MG 2 1607 |
| Chain | Residue |
| 2 | G591 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue MG 2 1608 |
| Chain | Residue |
| 2 | G727 |
| 2 | A726 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue MG 2 1609 |
| Chain | Residue |
| 2 | 6MZ1469 |
| 2 | G1474 |
| 2 | A1476 |
| 2 | G1477 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue MG 2 1610 |
| Chain | Residue |
| 2 | C106 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue MG 2 1611 |
| Chain | Residue |
| 2 | A148 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue MG 2 1612 |
| Chain | Residue |
| 2 | C584 |
| 2 | C586 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue MG 2 1616 |
| Chain | Residue |
| 2 | A1468 |
| 2 | 6MZ1469 |
| 2 | G1474 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue MG 2 1619 |
| Chain | Residue |
| 2 | A474 |
| 2 | A475 |
| site_id | AD6 |
| Number of Residues | 1 |
| Details | binding site for residue MG 2 1620 |
| Chain | Residue |
| 2 | C1373 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue MG 2 1621 |
| Chain | Residue |
| 2 | G554 |
| 2 | G555 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue MG 2 1622 |
| Chain | Residue |
| 2 | A112 |
| 2 | G113 |
| 2 | U114 |
| 2 | C298 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 101 |
| Chain | Residue |
| C | CYS32 |
| C | CYS35 |
| C | CYS55 |
| C | CYS58 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 102 |
| Chain | Residue |
| C | CYS14 |
| C | CYS17 |
| C | CYS43 |
| C | CYS46 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN F 301 |
| Chain | Residue |
| F | CYS128 |
| F | CYS133 |
| F | CYS135 |
| F | HIS139 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN R 201 |
| Chain | Residue |
| R | CYS16 |
| R | CYS21 |
| R | HIS24 |
| R | CYS77 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN W 101 |
| Chain | Residue |
| W | CYS20 |
| W | CYS23 |
| W | CYS39 |
| W | CYS42 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue MG 5 901 |
| Chain | Residue |
| 5 | U816 |
| 5 | A817 |
| site_id | AE6 |
| Number of Residues | 10 |
| Details | binding site for residues MA6 2 1487 and MA6 2 1488 |
| Chain | Residue |
| 0 | ARG22 |
| 2 | G758 |
| 2 | 5HM1378 |
| 2 | G1379 |
| 2 | U1380 |
| 2 | G1466 |
| 2 | UR31467 |
| 2 | G1485 |
| 2 | G1486 |
| 2 | C1489 |
Functional Information from PROSITE/UniProt
| site_id | PS00053 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_S8 Ribosomal protein S8 signature. GilIVSTSqGVMshkeAR |
| Chain | Residue | Details |
| I | GLY100-ARG117 |
| site_id | PS00054 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALarA.GLkIgrveDvTPiPHD |
| Chain | Residue | Details |
| M | ILE102-ASP124 |
| site_id | PS00056 |
| Number of Residues | 13 |
| Details | RIBOSOMAL_S17 Ribosomal protein S17 signature. GDrVlIaEtRPLS |
| Chain | Residue | Details |
| R | GLY83-SER95 |
| site_id | PS00362 |
| Number of Residues | 31 |
| Details | RIBOSOMAL_S15 Ribosomal protein S15 signature. LrkHLeqhPkDlhSmrgLqlIeskirrLvkY |
| Chain | Residue | Details |
| Q | LEU105-TYR135 |
| site_id | PS00528 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRLAaPtsWyIeR |
| Chain | Residue | Details |
| E | HIS9-ARG23 |
| site_id | PS00529 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S24E Ribosomal protein S24e signature. FGsyKSkGYAkYYYDkdrmlyiE |
| Chain | Residue | Details |
| V | PHE60-GLU82 |
| site_id | PS00578 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_S6E Ribosomal protein S6e signature. IRGGtDkdGfPM |
| Chain | Residue | Details |
| G | ILE63-MET74 |
| site_id | PS00585 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrvrFrVlaAVGNrd.GyVGlGighgr.EVgi.AI |
| Chain | Residue | Details |
| F | GLY78-ILE110 |
| site_id | PS00632 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtiVYKkglArTmrqARqLI |
| Chain | Residue | Details |
| D | LEU101-ILE125 |
| site_id | PS00962 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. LdQYLAAGVHIG |
| Chain | Residue | Details |
| B | LEU9-GLY20 |
| site_id | PS00963 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PdvIIItDpraDhqaMkEaieiGIP |
| Chain | Residue | Details |
| B | PRO112-PRO136 |
| site_id | PS01168 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_S27E Ribosomal protein S27e signature. KCidCgneqivFShPatrvrCnvCGatLvePtG |
| Chain | Residue | Details |
| W | LYS19-GLY51 |
| site_id | PS01191 |
| Number of Residues | 13 |
| Details | RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. VlNRVvEvTLkDI |
| Chain | Residue | Details |
| A | VAL44-ILE56 |
| site_id | PS01193 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_S8E Ribosomal protein S8e signature. RkpSGGrivla.RkKrKrELG |
| Chain | Residue | Details |
| J | ARG10-GLY29 |
| site_id | PS01262 |
| Number of Residues | 23 |
| Details | IF1A Eukaryotic initiation factor 1A signature. AlGaGWmdvrCeDGkiRrcRIpG |
| Chain | Residue | Details |
| 6 | ALA31-GLY53 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 71 |
| Details | Domain: {"description":"S4 RNA-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01306","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 62 |
| Details | Domain: {"description":"S4 RNA-binding"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 63 |
| Details | Domain: {"description":"S5 DRBM","evidences":[{"source":"HAMAP-Rule","id":"MF_01307","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 21 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 22 |
| Details | Zinc finger: {"description":"C4-type","evidences":[{"source":"HAMAP-Rule","id":"MF_00371","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00371","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
