6STJ

Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042981	biological_process	regulation of apoptotic process
B	0042981	biological_process	regulation of apoptotic process
C	0042981	biological_process	regulation of apoptotic process
D	0042981	biological_process	regulation of apoptotic process
E	0004869	molecular_function	cysteine-type endopeptidase inhibitor activity
F	0004869	molecular_function	cysteine-type endopeptidase inhibitor activity
G	0004869	molecular_function	cysteine-type endopeptidase inhibitor activity
H	0004869	molecular_function	cysteine-type endopeptidase inhibitor activity

Functional Information from PROSITE/UniProt

site_id	PS01080
Number of Residues	20
Details	BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFsDGvtNWGRIVTLIsFGA

Chain	Residue	Details
A	VAL253-ALA272

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site_id	PS01258
Number of Residues	12
Details	BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV

Chain	Residue	Details
A	TRP305-VAL316

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site_id	PS01259
Number of Residues	15
Details	BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AletLRrVGDGVQRN

Chain	Residue	Details
A	ALA209-ASN223

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)

Chain	Residue	Details
A	LYS194
D	LYS194
D	LYS197
A	LYS197
B	LYS194
B	LYS197
C	LYS194
C	LYS197

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