6SQZ
Mouse dCTPase in complex with dCMPNPP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0006253 | biological_process | dCTP catabolic process |
| A | 0009143 | biological_process | nucleoside triphosphate catabolic process |
| A | 0016462 | molecular_function | pyrophosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0032556 | molecular_function | pyrimidine deoxyribonucleotide binding |
| A | 0042262 | biological_process | DNA protection |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047429 | molecular_function | nucleoside triphosphate diphosphatase activity |
| A | 0047840 | molecular_function | dCTP diphosphatase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005829 | cellular_component | cytosol |
| D | 0006253 | biological_process | dCTP catabolic process |
| D | 0009143 | biological_process | nucleoside triphosphate catabolic process |
| D | 0016462 | molecular_function | pyrophosphatase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0032556 | molecular_function | pyrimidine deoxyribonucleotide binding |
| D | 0042262 | biological_process | DNA protection |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0047429 | molecular_function | nucleoside triphosphate diphosphatase activity |
| D | 0047840 | molecular_function | dCTP diphosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 201 |
| Chain | Residue |
| A | GLU63 |
| A | GLU66 |
| A | GLU95 |
| A | ASP98 |
| A | MG202 |
| A | 0KX203 |
| A | HOH311 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 202 |
| Chain | Residue |
| A | MG201 |
| A | 0KX203 |
| A | HOH330 |
| A | GLU63 |
| A | GLU66 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue 0KX A 203 |
| Chain | Residue |
| A | HIS38 |
| A | PHE41 |
| A | TRP47 |
| A | HIS51 |
| A | GLU63 |
| A | GLU66 |
| A | ASP98 |
| A | ILE101 |
| A | TYR102 |
| A | LYS121 |
| A | ASN125 |
| A | ARG128 |
| A | TYR129 |
| A | MG201 |
| A | MG202 |
| A | HOH311 |
| A | HOH314 |
| A | HOH344 |
| A | HOH345 |
| A | HOH356 |
| D | TRP73 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue MG D 201 |
| Chain | Residue |
| D | GLU63 |
| D | GLU66 |
| D | GLU95 |
| D | ASP98 |
| D | MG202 |
| D | 0KX203 |
| D | HOH303 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 202 |
| Chain | Residue |
| A | HOH322 |
| D | GLU63 |
| D | GLU66 |
| D | MG201 |
| D | 0KX203 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | binding site for residue 0KX D 203 |
| Chain | Residue |
| A | MET21 |
| A | TRP73 |
| A | HOH322 |
| D | HIS38 |
| D | TRP47 |
| D | HIS51 |
| D | GLU63 |
| D | GLU66 |
| D | ASP98 |
| D | ILE101 |
| D | TYR102 |
| D | LYS121 |
| D | ASN125 |
| D | ARG128 |
| D | TYR129 |
| D | MG201 |
| D | MG202 |
| D | HOH303 |
| D | HOH306 |
| D | HOH309 |
| D | HOH317 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17320107","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2OIG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17320107","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
