Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 501 |
| Chain | Residue |
| A | PHE66 |
| A | GLN67 |
| A | ASP76 |
| A | PHE77 |
| A | TYR78 |
| A | LYS202 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 502 |
| Chain | Residue |
| A | ALA180 |
| A | ARG341 |
| A | HOH935 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 503 |
| Chain | Residue |
| A | PRO441 |
| A | GLY443 |
| A | TRP463 |
| A | HOH906 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | MET56 |
| A | ALA350 |
| A | LEU473 |
| A | THR476 |
| A | HOH647 |
| A | HOH797 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | ILE38 |
| A | SER39 |
| A | ASP42 |
| A | TYR298 |
| A | HOH622 |
| A | HOH635 |
| A | HOH693 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | TYR100 |
| A | ARG104 |
| A | ASN162 |
| A | TYR175 |
| A | HOH645 |
| A | HOH680 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | THR97 |
| A | SER153 |
| A | LEU178 |
| A | LEU207 |
| A | HOH614 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | PRO417 |
| A | TRP418 |
| A | GLY419 |
| A | VAL420 |
| A | HOH665 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | ILE28 |
| A | GLU29 |
| A | EDO516 |
| B | LYS109 |
| B | ASN110 |
| B | HOH629 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 510 |
| Chain | Residue |
| A | GLY387 |
| A | ASN388 |
| A | SER394 |
| A | LEU462 |
| A | HOH744 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 511 |
| Chain | Residue |
| A | LYS197 |
| A | TRP198 |
| A | PRO211 |
| A | HOH690 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 512 |
| Chain | Residue |
| A | ASN148 |
| A | ILE252 |
| A | GLU254 |
| A | PHE320 |
| A | HOH706 |
| A | HOH747 |
| A | HOH750 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 513 |
| Chain | Residue |
| A | ILE30 |
| A | THR31 |
| A | HIS36 |
| A | TYR37 |
| A | THR403 |
| A | GLU404 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 514 |
| Chain | Residue |
| A | GLY168 |
| A | PHE173 |
| A | TYR175 |
| A | HOH657 |
| A | HOH783 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 515 |
| Chain | Residue |
| A | ASN424 |
| A | GLN455 |
| A | ASP456 |
| A | TRP457 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 516 |
| Chain | Residue |
| A | ILE28 |
| A | GLU29 |
| A | ILE30 |
| A | EDO509 |
| A | HOH840 |
| B | ASP319 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 517 |
| Chain | Residue |
| A | LYS109 |
| A | ASN110 |
| B | ILE28 |
| B | GLU29 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 518 |
| Chain | Residue |
| A | ASN61 |
| A | LEU231 |
| A | HOH603 |
| A | HOH653 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 519 |
| Chain | Residue |
| A | TYR100 |
| A | TYR101 |
| A | EDO520 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 520 |
| Chain | Residue |
| A | THR97 |
| A | EDO519 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 521 |
| Chain | Residue |
| A | VAL423 |
| A | ASN427 |
| A | GLN429 |
| A | LYS421 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue CL B 501 |
| Chain | Residue |
| B | PHE66 |
| B | GLN67 |
| B | ASP76 |
| B | PHE77 |
| B | TYR78 |
| B | LYS202 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 502 |
| Chain | Residue |
| B | PRO441 |
| B | GLY443 |
| B | TRP463 |
| B | HOH919 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 503 |
| Chain | Residue |
| B | ALA180 |
| B | ARG341 |
| B | HOH947 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| A | GLN32 |
| A | ASN306 |
| A | HOH674 |
| B | LYS238 |
| B | HOH654 |
| B | HOH661 |
| site_id | AE8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | HIS395 |
| B | PRO417 |
| B | TRP418 |
| B | GLY419 |
| B | VAL420 |
| B | EDO506 |
| B | HOH613 |
| B | HOH674 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | TYR313 |
| B | TRP315 |
| B | SER394 |
| B | EDO505 |
| B | HOH613 |
| B | HOH724 |
| B | HOH849 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 507 |
| Chain | Residue |
| B | ILE38 |
| B | SER39 |
| B | ASP42 |
| B | TYR298 |
| B | HOH672 |
| B | HOH734 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 508 |
| Chain | Residue |
| B | ASN88 |
| B | ASN89 |
| B | LYS92 |
| B | ASN426 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 509 |
| Chain | Residue |
| B | ASN148 |
| B | ILE252 |
| B | GLU254 |
| B | PHE320 |
| B | HOH661 |
| B | HOH707 |
| B | HOH753 |
| site_id | AF4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 510 |
| Chain | Residue |
| B | TYR100 |
| B | ARG104 |
| B | ASN162 |
| B | TYR175 |
| B | HOH616 |
| B | HOH687 |
| B | HOH867 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 511 |
| Chain | Residue |
| B | ASN95 |
| B | ARG99 |
| B | SER453 |
| B | ASP456 |
| B | HOH628 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 512 |
| Chain | Residue |
| B | LEU473 |
| B | THR474 |
| B | THR476 |
| B | HOH700 |
| B | HOH725 |
| B | HOH727 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 513 |
| Chain | Residue |
| B | LYS92 |
| B | ASN424 |
| B | GLN455 |
| B | ASP456 |
| B | TRP457 |
| site_id | AF8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 514 |
| Chain | Residue |
| A | HOH644 |
| B | PHE344 |
| B | HOH833 |
| site_id | AF9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 515 |
| Chain | Residue |
| B | MET56 |
| B | TRP338 |
| B | ALA350 |
| B | LEU473 |
| B | HOH612 |
| B | HOH725 |
| B | HOH773 |
| site_id | AG1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 516 |
| Chain | Residue |
| A | LYS238 |
| A | HOH750 |
| B | GLN32 |
| B | ASN306 |
| B | ILE309 |
| B | HOH777 |
| B | HOH789 |
| site_id | AG2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 517 |
| Chain | Residue |
| B | THR97 |
| B | SER153 |
| B | LEU178 |
| B | LEU207 |
| B | HOH630 |
| site_id | AG3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 518 |
| Chain | Residue |
| B | ASN75 |
| B | ASN89 |
| B | PHE131 |
| B | HOH643 |
| B | HOH798 |
| site_id | AG4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 519 |
| Chain | Residue |
| B | TYR37 |
| B | ILE38 |
| B | SER39 |
| B | HOH611 |
| B | HOH618 |
| B | HOH734 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 520 |
| Chain | Residue |
| B | SER105 |
| B | GLY106 |
| B | TYR107 |
| B | PRO113 |
| site_id | AG6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 521 |
| Chain | Residue |
| B | PHE35 |
| B | ILE38 |
| B | HIS40 |
| site_id | AG7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 522 |
| Chain | Residue |
| B | GLU124 |
| B | ASN125 |
| B | THR194 |
| B | ASP195 |
| B | HOH634 |
| B | HOH645 |
| B | HOH900 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 523 |
| Chain | Residue |
| B | THR97 |
| B | TYR100 |
| B | HOH820 |
| B | HOH956 |
| site_id | AG9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 524 |
| Chain | Residue |
| B | GLY387 |
| B | ASN388 |
| B | SER394 |
| B | HOH884 |
| site_id | AH1 |
| Number of Residues | 4 |
| Details | binding site for residue BCT B 525 |
| Chain | Residue |
| B | ILE30 |
| B | THR31 |
| B | THR403 |
| B | GLU404 |
