6SLZ
Crystal structure of human ROR gamma LBD in complex with a (quinolinoxymethyl)benzamide inverse agonist
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue LK8 A 601 |
| Chain | Residue |
| A | GLN286 |
| A | LEU396 |
| A | ILE400 |
| A | CYS476 |
| A | LEU483 |
| A | HOH715 |
| A | HOH717 |
| A | HOH768 |
| A | TRP317 |
| A | CYS320 |
| A | HIS323 |
| A | LEU324 |
| A | ALA327 |
| A | LEU362 |
| A | PHE378 |
| A | PHE388 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue LK8 B 601 |
| Chain | Residue |
| B | GLN286 |
| B | CYS320 |
| B | HIS323 |
| B | LEU324 |
| B | ALA327 |
| B | PHE377 |
| B | PHE378 |
| B | PHE388 |
| B | LEU396 |
| B | ILE400 |
| B | CYS476 |
| B | LEU483 |
| B | HOH709 |
| B | HOH715 |
