6SKU

Legionella effector AnkX in complex with human Rab1b

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0044605	molecular_function	phosphocholine transferase activity
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue GDP B 201

Chain	Residue
B	SER16
B	ASN120
B	LYS121
B	ASP123
B	LEU124
B	SER150
B	ALA151
B	LYS152
B	MG202
B	GLY17
B	VAL18
B	GLY19
B	LYS20
B	SER21
B	CYS22
B	TYR32
B	GLU34

---

site_id	AC2
Number of Residues	4
Details	binding site for residue MG B 202

Chain	Residue
B	SER21
B	ASP62
B	THR63
B	GDP201

---

Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. LLLiGDSGVGKscL

Chain	Residue	Details
B	LEU10-LEU23

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	134
Details	Domain: {"description":"Fido","evidences":[{"source":"PROSITE-ProRule","id":"PRU00791","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	29
Details	Repeat: {"description":"ANK 1"}

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Residue

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site_id	SWS_FT_FI3
Number of Residues	29
Details	Repeat: {"description":"ANK 2"}

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site_id	SWS_FT_FI4
Number of Residues	30
Details	Repeat: {"description":"ANK 3"}

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Residue

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site_id	SWS_FT_FI5
Number of Residues	29
Details	Repeat: {"description":"ANK 4"}

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site_id	SWS_FT_FI6
Number of Residues	29
Details	Repeat: {"description":"ANK 5"}

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Residue

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site_id	SWS_FT_FI7
Number of Residues	29
Details	Repeat: {"description":"ANK 6"}

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Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	29
Details	Repeat: {"description":"ANK 7"}

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Residue

Details

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site_id	SWS_FT_FI9
Number of Residues	29
Details	Repeat: {"description":"ANK 8"}

Chain

Residue

Details

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site_id	SWS_FT_FI10
Number of Residues	42
Details	Repeat: {"description":"ANK 9"}

Chain

Residue

Details

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site_id	SWS_FT_FI11
Number of Residues	29
Details	Repeat: {"description":"ANK 10"}

Chain

Residue

Details

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site_id	SWS_FT_FI12
Number of Residues	15
Details	Motif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"20064470","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3JZA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20651120","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27552051","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3NKV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SZH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SZK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27552051","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5SZH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SZK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"3NKV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20651120","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23236136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27552051","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3NKV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4HLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4I1O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SZH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SZK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27552051","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5SZH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20651120","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3NKV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23236136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27552051","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4HLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SZH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI20
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27552051","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5SZK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI21
Number of Residues	1
Details	Modified residue: {"description":"(Microbial infection) O-(2-cholinephosphoryl)serine","evidences":[{"source":"PubMed","id":"21822290","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22158903","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22307087","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	Modified residue: {"description":"(Microbial infection) O-AMP-tyrosine","evidences":[{"source":"PubMed","id":"20651120","evidenceCode":"ECO:0000269"}]}

Chain

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