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6SJA

Structure of HPV16 E6 oncoprotein in complex with IRF3 LxxLL motif

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0006974biological_processDNA damage response
A0008643biological_processcarbohydrate transport
A0015144molecular_functioncarbohydrate transmembrane transporter activity
A0015768biological_processmaltose transport
A0016020cellular_componentmembrane
A0030288cellular_componentouter membrane-bounded periplasmic space
A0034219biological_processcarbohydrate transmembrane transport
A0034289biological_processdetection of maltose stimulus
A0042597cellular_componentperiplasmic space
A0042956biological_processmaltodextrin transmembrane transport
A0043190cellular_componentATP-binding cassette (ABC) transporter complex
A0055052cellular_componentATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A0055085biological_processtransmembrane transport
A0060326biological_processcell chemotaxis
A1901982molecular_functionmaltose binding
A1990060cellular_componentmaltose transport complex
B0003677molecular_functionDNA binding
B0005515molecular_functionprotein binding
B0006351biological_processDNA-templated transcription
B0006355biological_processregulation of DNA-templated transcription
B0019049biological_processvirus-mediated perturbation of host defense response
B0030162biological_processregulation of proteolysis
B0030165molecular_functionPDZ domain binding
B0030430cellular_componenthost cell cytoplasm
B0039502biological_processsymbiont-mediated suppression of host type I interferon-mediated signaling pathway
B0039548biological_processsymbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity
B0039648biological_processsymbiont-mediated perturbation of host ubiquitin-like protein modification
B0039653biological_processsymbiont-mediated suppression of host transcription
B0042025cellular_componenthost cell nucleus
B0042802molecular_functionidentical protein binding
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0046872molecular_functionmetal ion binding
B0052150biological_processsymbiont-mediated perturbation of host apoptosis
B0090630biological_processactivation of GTPase activity
Functional Information from PROSITE/UniProt
site_idPS01037
Number of Residues18
DetailsSBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN
ChainResidueDetails
APRO108-ASN125

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues72
DetailsZN_FING: ZN_FING => ECO:0000255|HAMAP-Rule:MF_04006
ChainResidueDetails
BCYS1030-CYS1066
BCYS1103-CYS1139

227111

PDB entries from 2024-11-06

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