6SJ6
Cryo-EM structure of 50S-RsfS complex from Staphylococcus aureus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| 0 | 0003735 | molecular_function | structural constituent of ribosome |
| 0 | 0005840 | cellular_component | ribosome |
| 0 | 0006412 | biological_process | translation |
| 0 | 1990904 | cellular_component | ribonucleoprotein complex |
| 1 | 0003735 | molecular_function | structural constituent of ribosome |
| 1 | 0005840 | cellular_component | ribosome |
| 1 | 0006412 | biological_process | translation |
| 1 | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| 1 | 1990904 | cellular_component | ribonucleoprotein complex |
| 2 | 0003735 | molecular_function | structural constituent of ribosome |
| 2 | 0005840 | cellular_component | ribosome |
| 2 | 0006412 | biological_process | translation |
| 2 | 0015934 | cellular_component | large ribosomal subunit |
| 2 | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| 2 | 1990904 | cellular_component | ribonucleoprotein complex |
| 4 | 0003735 | molecular_function | structural constituent of ribosome |
| 4 | 0005840 | cellular_component | ribosome |
| 4 | 0006412 | biological_process | translation |
| 4 | 0015934 | cellular_component | large ribosomal subunit |
| 4 | 1990904 | cellular_component | ribonucleoprotein complex |
| 6 | 0003735 | molecular_function | structural constituent of ribosome |
| 6 | 0005840 | cellular_component | ribosome |
| 6 | 0006412 | biological_process | translation |
| 6 | 1990904 | cellular_component | ribonucleoprotein complex |
| 7 | 0003735 | molecular_function | structural constituent of ribosome |
| 7 | 0005840 | cellular_component | ribosome |
| 7 | 0006412 | biological_process | translation |
| 7 | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| 7 | 1990904 | cellular_component | ribonucleoprotein complex |
| 9 | 0005737 | cellular_component | cytoplasm |
| 9 | 0006417 | biological_process | regulation of translation |
| 9 | 0017148 | biological_process | negative regulation of translation |
| 9 | 0042256 | biological_process | cytosolic ribosome assembly |
| 9 | 0043023 | molecular_function | ribosomal large subunit binding |
| 9 | 0090071 | biological_process | negative regulation of ribosome biogenesis |
| D | 0002181 | biological_process | cytoplasmic translation |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003735 | molecular_function | structural constituent of ribosome |
| D | 0005840 | cellular_component | ribosome |
| D | 0006412 | biological_process | translation |
| D | 0015934 | cellular_component | large ribosomal subunit |
| D | 0016740 | molecular_function | transferase activity |
| D | 0019843 | molecular_function | rRNA binding |
| D | 1990904 | cellular_component | ribonucleoprotein complex |
| E | 0003723 | molecular_function | RNA binding |
| E | 0003735 | molecular_function | structural constituent of ribosome |
| E | 0005840 | cellular_component | ribosome |
| E | 0006412 | biological_process | translation |
| E | 0019843 | molecular_function | rRNA binding |
| E | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| E | 1990904 | cellular_component | ribonucleoprotein complex |
| F | 0003723 | molecular_function | RNA binding |
| F | 0003735 | molecular_function | structural constituent of ribosome |
| F | 0005840 | cellular_component | ribosome |
| F | 0006412 | biological_process | translation |
| F | 0019843 | molecular_function | rRNA binding |
| F | 1990904 | cellular_component | ribonucleoprotein complex |
| M | 0003729 | molecular_function | mRNA binding |
| M | 0003735 | molecular_function | structural constituent of ribosome |
| M | 0005840 | cellular_component | ribosome |
| M | 0006412 | biological_process | translation |
| M | 0017148 | biological_process | negative regulation of translation |
| M | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| M | 1990904 | cellular_component | ribonucleoprotein complex |
| N | 0003723 | molecular_function | RNA binding |
| N | 0003735 | molecular_function | structural constituent of ribosome |
| N | 0005840 | cellular_component | ribosome |
| N | 0006412 | biological_process | translation |
| N | 0015934 | cellular_component | large ribosomal subunit |
| N | 0019843 | molecular_function | rRNA binding |
| N | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| N | 0070180 | molecular_function | large ribosomal subunit rRNA binding |
| N | 1990904 | cellular_component | ribonucleoprotein complex |
| O | 0003723 | molecular_function | RNA binding |
| O | 0003735 | molecular_function | structural constituent of ribosome |
| O | 0005840 | cellular_component | ribosome |
| O | 0006412 | biological_process | translation |
| O | 0015934 | cellular_component | large ribosomal subunit |
| O | 0019843 | molecular_function | rRNA binding |
| O | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| O | 1990904 | cellular_component | ribonucleoprotein complex |
| P | 0000049 | molecular_function | tRNA binding |
| P | 0003723 | molecular_function | RNA binding |
| P | 0003735 | molecular_function | structural constituent of ribosome |
| P | 0005840 | cellular_component | ribosome |
| P | 0006412 | biological_process | translation |
| P | 0019843 | molecular_function | rRNA binding |
| P | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| P | 1990904 | cellular_component | ribonucleoprotein complex |
| Q | 0003735 | molecular_function | structural constituent of ribosome |
| Q | 0005840 | cellular_component | ribosome |
| Q | 0006412 | biological_process | translation |
| Q | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| Q | 1990904 | cellular_component | ribonucleoprotein complex |
| R | 0003723 | molecular_function | RNA binding |
| R | 0003735 | molecular_function | structural constituent of ribosome |
| R | 0005737 | cellular_component | cytoplasm |
| R | 0005840 | cellular_component | ribosome |
| R | 0006412 | biological_process | translation |
| R | 0008097 | molecular_function | 5S rRNA binding |
| R | 0019843 | molecular_function | rRNA binding |
| R | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| R | 1990904 | cellular_component | ribonucleoprotein complex |
| S | 0003735 | molecular_function | structural constituent of ribosome |
| S | 0005840 | cellular_component | ribosome |
| S | 0006412 | biological_process | translation |
| S | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| S | 1990904 | cellular_component | ribonucleoprotein complex |
| T | 0000027 | biological_process | ribosomal large subunit assembly |
| T | 0003723 | molecular_function | RNA binding |
| T | 0003735 | molecular_function | structural constituent of ribosome |
| T | 0005840 | cellular_component | ribosome |
| T | 0006412 | biological_process | translation |
| T | 0019843 | molecular_function | rRNA binding |
| T | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| T | 1990904 | cellular_component | ribonucleoprotein complex |
| U | 0003723 | molecular_function | RNA binding |
| U | 0003735 | molecular_function | structural constituent of ribosome |
| U | 0005737 | cellular_component | cytoplasm |
| U | 0005840 | cellular_component | ribosome |
| U | 0006412 | biological_process | translation |
| U | 0019843 | molecular_function | rRNA binding |
| U | 1990904 | cellular_component | ribonucleoprotein complex |
| V | 0003723 | molecular_function | RNA binding |
| V | 0003735 | molecular_function | structural constituent of ribosome |
| V | 0005840 | cellular_component | ribosome |
| V | 0006412 | biological_process | translation |
| V | 0015934 | cellular_component | large ribosomal subunit |
| V | 0019843 | molecular_function | rRNA binding |
| V | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| V | 1990904 | cellular_component | ribonucleoprotein complex |
| W | 0003723 | molecular_function | RNA binding |
| W | 0003735 | molecular_function | structural constituent of ribosome |
| W | 0005840 | cellular_component | ribosome |
| W | 0006412 | biological_process | translation |
| W | 0019843 | molecular_function | rRNA binding |
| W | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| W | 1990904 | cellular_component | ribonucleoprotein complex |
| X | 0003723 | molecular_function | RNA binding |
| X | 0003735 | molecular_function | structural constituent of ribosome |
| X | 0005840 | cellular_component | ribosome |
| X | 0006412 | biological_process | translation |
| X | 0019843 | molecular_function | rRNA binding |
| X | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| X | 1990904 | cellular_component | ribonucleoprotein complex |
| Y | 0003723 | molecular_function | RNA binding |
| Y | 0003735 | molecular_function | structural constituent of ribosome |
| Y | 0005840 | cellular_component | ribosome |
| Y | 0006412 | biological_process | translation |
| Y | 0008097 | molecular_function | 5S rRNA binding |
| Y | 0019843 | molecular_function | rRNA binding |
| Y | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| Y | 1990904 | cellular_component | ribonucleoprotein complex |
| Z | 0003735 | molecular_function | structural constituent of ribosome |
| Z | 0005840 | cellular_component | ribosome |
| Z | 0006412 | biological_process | translation |
| Z | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| Z | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3001 |
| Chain | Residue |
| A | U1287 |
| A | G1288 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3003 |
| Chain | Residue |
| A | G2083 |
| A | G2084 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3005 |
| Chain | Residue |
| A | U610 |
| A | G854 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3006 |
| Chain | Residue |
| A | C1351 |
| A | C1352 |
| A | G1369 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3007 |
| Chain | Residue |
| A | G2056 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3008 |
| Chain | Residue |
| A | G2482 |
| A | U2518 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3009 |
| Chain | Residue |
| A | G2521 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3010 |
| Chain | Residue |
| A | G2522 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3011 |
| Chain | Residue |
| A | U1007 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3012 |
| Chain | Residue |
| A | G613 |
| A | A2475 |
| A | C2526 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3013 |
| Chain | Residue |
| A | U614 |
| A | A618 |
| A | A2057 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3014 |
| Chain | Residue |
| A | G620 |
| A | A621 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3017 |
| Chain | Residue |
| A | G863 |
| A | G1226 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3018 |
| Chain | Residue |
| A | A1034 |
| A | C1035 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3019 |
| Chain | Residue |
| A | A1199 |
| A | A1200 |
| A | G1201 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3020 |
| Chain | Residue |
| A | A1228 |
| A | G1229 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3021 |
| Chain | Residue |
| A | U987 |
| O | HIS35 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3022 |
| Chain | Residue |
| A | C789 |
| site_id | AE1 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3023 |
| Chain | Residue |
| A | A1303 |
| A | U2642 |
| site_id | AE2 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3025 |
| Chain | Residue |
| A | U1305 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3026 |
| Chain | Residue |
| A | A1306 |
| A | C2033 |
| site_id | AE4 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3027 |
| Chain | Residue |
| A | G2059 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3030 |
| Chain | Residue |
| A | G2088 |
| A | G2529 |
| site_id | AE6 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3031 |
| Chain | Residue |
| A | A2089 |
| site_id | AE7 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3032 |
| Chain | Residue |
| A | U1011 |
| site_id | AE8 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3033 |
| Chain | Residue |
| A | U964 |
| site_id | AE9 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3034 |
| Chain | Residue |
| A | A963 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3035 |
| Chain | Residue |
| A | C2275 |
| A | U2276 |
| site_id | AF2 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3037 |
| Chain | Residue |
| A | G192 |
| site_id | AF3 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3038 |
| Chain | Residue |
| A | C31 |
| site_id | AF4 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3039 |
| Chain | Residue |
| A | A1275 |
| site_id | AF5 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3040 |
| Chain | Residue |
| A | A343 |
| A | G381 |
| site_id | AF6 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3042 |
| Chain | Residue |
| A | G1329 |
| site_id | AF7 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3043 |
| Chain | Residue |
| A | C1334 |
| A | U1683 |
| site_id | AF8 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3044 |
| Chain | Residue |
| A | C1335 |
| A | U1683 |
| site_id | AF9 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3045 |
| Chain | Residue |
| A | U1680 |
| site_id | AG1 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3046 |
| Chain | Residue |
| A | A1786 |
| site_id | AG2 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3047 |
| Chain | Residue |
| A | A847 |
| site_id | AG3 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3048 |
| Chain | Residue |
| A | A845 |
| site_id | AG4 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3049 |
| Chain | Residue |
| A | G496 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 3050 |
| Chain | Residue |
| A | C861 |
| A | C862 |
| A | G1225 |
| A | G1226 |
| site_id | AG6 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3051 |
| Chain | Residue |
| A | G1803 |
| site_id | AG7 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3052 |
| Chain | Residue |
| A | A775 |
| A | C776 |
| A | A806 |
| site_id | AG8 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3053 |
| Chain | Residue |
| A | A660 |
| A | U661 |
| F | ARG106 |
| site_id | AG9 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3054 |
| Chain | Residue |
| 4 | LEU39 |
| A | C2836 |
| site_id | AH1 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3055 |
| Chain | Residue |
| A | C777 |
| site_id | AH2 |
| Number of Residues | 2 |
| Details | binding site for residue K A 3057 |
| Chain | Residue |
| A | C1714 |
| A | U1715 |
| site_id | AH3 |
| Number of Residues | 1 |
| Details | binding site for residue K A 3059 |
| Chain | Residue |
| A | A880 |
Functional Information from PROSITE/UniProt
| site_id | PS00049 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L14 Ribosomal protein L14 signature. AVIVrtksgvrrn.DGsyikFdeNacVI |
| Chain | Residue | Details |
| N | ALA60-ILE86 |
| site_id | PS00464 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_L22 Ribosomal protein L22 signature. KrfRpRAqGRasainkrtSHITIvV |
| Chain | Residue | Details |
| V | LYS83-VAL107 |
| site_id | PS00467 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGSVmNPnD |
| Chain | Residue | Details |
| D | PRO217-ASP228 |
| site_id | PS00474 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L3 Ribosomal protein L3 signature. FvagdviDvtGvSkGKGfqGaikR |
| Chain | Residue | Details |
| E | PHE110-ARG133 |
| site_id | PS00475 |
| Number of Residues | 31 |
| Details | RIBOSOMAL_L15 Ribosomal protein L15 signature. KILGnGsLdkk..LtVkahkFSasAaeaIdakG |
| Chain | Residue | Details |
| O | LYS110-GLY140 |
| site_id | PS00586 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRgGKVWIKIFP |
| Chain | Residue | Details |
| P | LYS59-PRO70 |
| site_id | PS00591 |
| Number of Residues | 11 |
| Details | GH10_1 Glycosyl hydrolases family 10 (GH10) active site. AIEVdITELNI |
| Chain | Residue | Details |
| Y | ALA140-ILE150 |
| site_id | PS00701 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGaGKGavegW |
| Chain | Residue | Details |
| P | ARG82-TRP93 |
| site_id | PS00783 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_L13 Ribosomal protein L13 signature. IKGMLPstrl.GEkqgkkLfVYgG |
| Chain | Residue | Details |
| M | ILE106-GLY128 |
| site_id | PS00784 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTYQpnkrkHskvh.GFrkR |
| Chain | Residue | Details |
| 6 | LYS3-ARG22 |
| site_id | PS00831 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L27 Ribosomal protein L27 signature. GsILyRQRGtkiypG |
| Chain | Residue | Details |
| Z | GLY42-GLY56 |
| site_id | PS00936 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHrGAaKRVkrtasgqlkrsraft.SH |
| Chain | Residue | Details |
| 7 | LYS5-HIS31 |
| site_id | PS00937 |
| Number of Residues | 17 |
| Details | RIBOSOMAL_L20 Ribosomal protein L20 signature. KrdfRkLWITRINaaaR |
| Chain | Residue | Details |
| T | LYS54-ARG70 |
| site_id | PS01015 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGKVR.RAKLYYLR |
| Chain | Residue | Details |
| S | VAL88-ARG103 |
| site_id | PS01108 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L24 Ribosomal protein L24 signature. GDnVkVIaGkdKGke.GkV |
| Chain | Residue | Details |
| X | GLY6-VAL23 |
| site_id | PS01167 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_L17 Ribosomal protein L17 signature. IeTTeaRaKevrsvvEkLITlGK |
| Chain | Residue | Details |
| Q | ILE30-LYS52 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 168 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 17 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Compositional bias: {"description":"Gly residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 40 |
| Details | Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
