Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016571 | biological_process | histone methylation |
| A | 0035098 | cellular_component | ESC/E(Z) complex |
| B | 0016571 | biological_process | histone methylation |
| B | 0035098 | cellular_component | ESC/E(Z) complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 501 |
| Chain | Residue |
| A | ASP341 |
| A | CA502 |
| A | HOH703 |
| A | HOH842 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 502 |
| Chain | Residue |
| A | ASP339 |
| A | ASP341 |
| A | CA501 |
| A | HOH783 |
| A | HOH842 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue L9W A 503 |
| Chain | Residue |
| A | PHE97 |
| A | TYR148 |
| A | ASN194 |
| A | LYS211 |
| A | LEU240 |
| A | LYS284 |
| A | THR285 |
| A | ASP310 |
| A | TYR365 |
| A | MET366 |
| A | ARG367 |
| A | ARG414 |
| A | HOH601 |
| A | HOH696 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue L9T B 501 |
| Chain | Residue |
| B | PHE97 |
| B | TYR148 |
| B | ASN194 |
| B | LEU240 |
| B | ASP310 |
| B | TYR365 |
| B | MET366 |
| B | ARG367 |
| B | ARG414 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSVskDhALRLWNI |
| Chain | Residue | Details |
| A | LEU206-ILE220 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 86 |
| Details | Repeat: {"description":"WD 1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 86 |
| Details | Repeat: {"description":"WD 2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"WD 3"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 82 |
| Details | Repeat: {"description":"WD 4"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 74 |
| Details | Repeat: {"description":"WD 5"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 154 |
| Details | Region: {"description":"Required for interaction with the matrix protein MA of HIV-1"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 5 |
| Details | Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"20974918","evidenceCode":"ECO:0000269"}]} |
