6SCY
U34-tRNA thiolase NcsA from Methanococcus maripaludis with its [4Fe-4S] cluster
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0002098 | biological_process | tRNA wobble uridine modification |
| A | 0002143 | biological_process | tRNA wobble position uridine thiolation |
| A | 0002144 | cellular_component | cytosolic tRNA wobble base thiouridylase complex |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008033 | biological_process | tRNA processing |
| A | 0016740 | molecular_function | transferase activity |
| A | 0034227 | biological_process | tRNA thio-modification |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0002098 | biological_process | tRNA wobble uridine modification |
| B | 0002143 | biological_process | tRNA wobble position uridine thiolation |
| B | 0002144 | cellular_component | cytosolic tRNA wobble base thiouridylase complex |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008033 | biological_process | tRNA processing |
| B | 0016740 | molecular_function | transferase activity |
| B | 0034227 | biological_process | tRNA thio-modification |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | CYS6 |
| A | CYS9 |
| A | CYS25 |
| A | CYS28 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 402 |
| Chain | Residue |
| A | CYS282 |
| A | CYS285 |
| A | CYS297 |
| A | LEU300 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 A 403 |
| Chain | Residue |
| A | ARG94 |
| A | CYS142 |
| A | CYS145 |
| A | ARG149 |
| A | CYS233 |
| A | SER236 |
| A | SO4405 |
| A | GLU88 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | ARG150 |
| A | HIS169 |
| A | ARG205 |
| A | LYS207 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | ARG149 |
| A | SF4403 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | ILE183 |
| A | GLU184 |
| A | HOH513 |
| A | HOH529 |
| B | HIS255 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 407 |
| Chain | Residue |
| A | TYR112 |
| A | SO4418 |
| B | ARG38 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 408 |
| Chain | Residue |
| A | HIS255 |
| A | HOH511 |
| B | GLU184 |
| B | PHE240 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 409 |
| Chain | Residue |
| A | LYS5 |
| A | TYR93 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 410 |
| Chain | Residue |
| A | SER57 |
| A | GLY59 |
| A | LYS60 |
| A | ASP61 |
| A | SER62 |
| A | SO4411 |
| A | HOH505 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 411 |
| Chain | Residue |
| A | SER57 |
| A | ILE167 |
| A | GLY168 |
| A | HIS169 |
| A | SO4410 |
| A | SO4425 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 412 |
| Chain | Residue |
| A | ARG155 |
| A | HOH514 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 413 |
| Chain | Residue |
| A | TYR120 |
| A | LYS151 |
| A | ILE152 |
| A | ARG155 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 414 |
| Chain | Residue |
| A | GLY42 |
| A | ARG43 |
| A | SO4422 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 415 |
| Chain | Residue |
| A | ASN48 |
| A | ASN49 |
| A | HOH508 |
| B | LYS5 |
| B | THR95 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 416 |
| Chain | Residue |
| A | LYS26 |
| A | LEU224 |
| A | SO4419 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 417 |
| Chain | Residue |
| A | TYR15 |
| A | HIS16 |
| B | ILE2 |
| B | THR3 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 418 |
| Chain | Residue |
| A | TYR112 |
| A | SO4407 |
| B | ARG38 |
| B | TYR72 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 419 |
| Chain | Residue |
| A | LYS26 |
| A | GLU225 |
| A | SO4416 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 420 |
| Chain | Residue |
| A | ARG155 |
| A | ILE284 |
| A | CYS285 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 422 |
| Chain | Residue |
| A | ARG43 |
| A | SO4414 |
| A | HOH515 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 423 |
| Chain | Residue |
| A | LYS8 |
| A | LYS31 |
| A | HOH530 |
| site_id | AE5 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 424 |
| Chain | Residue |
| A | HIS272 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 425 |
| Chain | Residue |
| A | ARG149 |
| A | HIS169 |
| A | ARG205 |
| A | SO4411 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 401 |
| Chain | Residue |
| B | CYS6 |
| B | CYS9 |
| B | CYS25 |
| B | CYS28 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 402 |
| Chain | Residue |
| B | CYS282 |
| B | CYS285 |
| B | CYS294 |
| B | CYS297 |
| site_id | AE9 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 B 403 |
| Chain | Residue |
| B | GLU88 |
| B | ARG94 |
| B | CYS142 |
| B | CYS145 |
| B | ARG149 |
| B | CYS233 |
| B | SER236 |
| B | SO4407 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 404 |
| Chain | Residue |
| B | GLY146 |
| B | ARG149 |
| B | HIS169 |
| B | ARG205 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 405 |
| Chain | Residue |
| B | ARG150 |
| B | HIS169 |
| B | LEU193 |
| B | ARG205 |
| B | LYS207 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 406 |
| Chain | Residue |
| B | ARG35 |
| B | LYS39 |
| B | SO4415 |
| B | HOH511 |
| site_id | AF4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 407 |
| Chain | Residue |
| B | ARG94 |
| B | SF4403 |
| B | SO4417 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 408 |
| Chain | Residue |
| B | SER57 |
| B | GLY59 |
| B | ASP61 |
| B | SER62 |
| B | SO4417 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 409 |
| Chain | Residue |
| B | LYS26 |
| B | MET223 |
| B | LEU224 |
| B | HOH510 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 410 |
| Chain | Residue |
| B | LYS60 |
| B | ASP61 |
| B | GLU214 |
| B | HOH512 |
| B | HOH525 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 411 |
| Chain | Residue |
| A | GLU71 |
| B | LYS113 |
| B | SO4412 |
| B | HOH550 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 412 |
| Chain | Residue |
| B | GLU159 |
| B | GLU160 |
| B | SO4411 |
| B | HOH505 |
| site_id | AG1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 413 |
| Chain | Residue |
| B | SER239 |
| B | GLU243 |
| B | HOH514 |
| site_id | AG2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 414 |
| Chain | Residue |
| B | HIS16 |
| B | LYS18 |
| B | HOH538 |
| site_id | AG3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 415 |
| Chain | Residue |
| B | LYS36 |
| B | SO4406 |
| B | SO4425 |
| B | HOH527 |
| site_id | AG4 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 B 416 |
| Chain | Residue |
| B | LYS18 |
| site_id | AG5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 417 |
| Chain | Residue |
| B | SER57 |
| B | ARG149 |
| B | SO4407 |
| B | SO4408 |
| B | SO4422 |
| B | HOH549 |
| site_id | AG6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 418 |
| Chain | Residue |
| B | LYS204 |
| B | ARG205 |
| B | LYS207 |
| B | GLU210 |
| site_id | AG7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 419 |
| Chain | Residue |
| B | ASP44 |
| B | LYS47 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 420 |
| Chain | Residue |
| B | TYR120 |
| B | GLU159 |
| B | LYS308 |
| B | HOH518 |
| site_id | AG9 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 421 |
| Chain | Residue |
| B | LYS253 |
| B | HOH507 |
| B | HOH515 |
| B | HOH519 |
| B | HOH546 |
| site_id | AH1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 422 |
| Chain | Residue |
| B | HIS169 |
| B | ASP173 |
| B | ARG241 |
| B | SO4417 |
| B | HOH523 |
| B | HOH541 |
| site_id | AH2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 423 |
| Chain | Residue |
| B | TYR120 |
| B | LYS151 |
| B | ILE152 |
| B | ARG155 |
| B | LYS308 |
| site_id | AH3 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 B 424 |
| Chain | Residue |
| B | ASN250 |
| site_id | AH4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 425 |
| Chain | Residue |
| B | GLN17 |
| B | TYR24 |
| B | ARG35 |
| B | LYS36 |
| B | SO4415 |
| B | HOH513 |
| site_id | AH5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 426 |
| Chain | Residue |
| A | LYS161 |
| B | LYS26 |
| B | GLU27 |
| B | HOH524 |
