6S8Y

Crystal structure of cytochrome c in complex with a sulfonated quinoline-derived foldamer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005758	cellular_component	mitochondrial intermembrane space
A	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
A	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
A	0009055	molecular_function	electron transfer activity
A	0020037	molecular_function	heme binding
A	0022904	biological_process	respiratory electron transport chain
A	0046872	molecular_function	metal ion binding
A	1901612	molecular_function	cardiolipin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue HEC A 201

Chain	Residue
A	ARG13
A	GLY41
A	TYR46
A	TYR48
A	THR49
A	ASN52
A	TRP59
A	MET64
A	TYR67
A	THR78
A	LYS79
A	CYS14
A	MET80
A	PHE82
A	HOH305
A	CYS17
A	HIS18
A	VAL28
A	GLY29
A	PRO30
A	ILE35
A	SER40

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 202

Chain	Residue
A	HIS33
A	GLU103
A	ACT204
A	HOH319

---

site_id	AC3
Number of Residues	6
Details	binding site for residue ZN A 203

Chain	Residue
A	HIS39
A	HIS39
A	ACT205
A	ACT205
A	HOH301
A	HOH301

---

site_id	AC4
Number of Residues	6
Details	binding site for residue ACT A 204

Chain	Residue
A	LYS22
A	HIS33
A	GLU103
A	ZN202
A	HOH306
A	HOH319

---

site_id	AC5
Number of Residues	6
Details	binding site for residue ACT A 205

Chain	Residue
A	HIS39
A	HIS39
A	ZN203
A	ZN203
A	HOH301
A	HOH301

---

site_id	AC6
Number of Residues	10
Details	binding site for residue L0T A 206

Chain	Residue
A	LYS4
A	ASN70
A	LYS72
A	GLY83
A	LYS86
A	LYS100
A	L0T207
A	ZN208
A	HOH309
A	HOH314

---

site_id	AC7
Number of Residues	15
Details	binding site for residue L0T A 207

Chain	Residue
A	LYS5
A	PRO25
A	HIS26
A	LYS27
A	THR69
A	ASN70
A	LYS73
A	LYS86
A	LYS87
A	LYS89
A	LYS100
A	L0T206
A	ZN208
A	HOH317
A	HOH321

---

site_id	AC8
Number of Residues	2
Details	binding site for residue ZN A 208

Chain	Residue
A	L0T206
A	L0T207

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CX5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CX5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6,N6,N6-trimethyllysine; by CTM1","evidences":[{"source":"PubMed","id":"10791961","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"source":"PubMed","id":"10821864","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---