6S8N
Cryo-EM structure of LptB2FGC in complex with lipopolysaccharide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0015221 | molecular_function | lipopolysaccharide transmembrane transporter activity |
| C | 0015920 | biological_process | lipopolysaccharide transport |
| C | 0017089 | molecular_function | glycolipid transfer activity |
| C | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| C | 0043165 | biological_process | Gram-negative-bacterium-type cell outer membrane assembly |
| C | 0046836 | biological_process | glycolipid transport |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0015920 | biological_process | lipopolysaccharide transport |
| F | 0016020 | cellular_component | membrane |
| F | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| F | 0055085 | biological_process | transmembrane transport |
| G | 0005886 | cellular_component | plasma membrane |
| G | 0015920 | biological_process | lipopolysaccharide transport |
| G | 0016020 | cellular_component | membrane |
| G | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| G | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue DCQ B 301 |
| Chain | Residue |
| B | ARG91 |
| B | MET134 |
| B | GLY135 |
| B | GLN136 |
| F | LYS78 |
| F | THR81 |
| F | GLU82 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue LMN F 401 |
| Chain | Residue |
| C | ILE10 |
| C | SER13 |
| F | LEU297 |
| G | ILE32 |
| G | L0W401 |
| G | LMN402 |
| C | MET1 |
| C | ARG6 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue LMT F 402 |
| Chain | Residue |
| F | ARG295 |
| F | MET299 |
| G | LMT403 |
| G | DCQ404 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue L0W G 401 |
| Chain | Residue |
| F | ILE25 |
| F | ARG33 |
| F | LMN401 |
| G | ILE66 |
| G | PHE67 |
| G | PRO69 |
| G | SER314 |
| G | PHE317 |
| G | PHE319 |
| G | TYR320 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue LMN G 402 |
| Chain | Residue |
| F | GLN293 |
| F | GLY294 |
| F | LMN401 |
| G | MET25 |
| G | PRO304 |
| G | MET305 |
| G | GLY306 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue LMT G 403 |
| Chain | Residue |
| F | LMT402 |
| G | PRO299 |
| G | LEU300 |
| G | VAL307 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue DCQ G 404 |
| Chain | Residue |
| F | LMT402 |
| G | SER314 |
Functional Information from PROSITE/UniProt
| site_id | PS00211 |
| Number of Residues | 15 |
| Details | ABC_TRANSPORTER_1 ABC transporters family signature. LSGGERRRVEIARAL |
| Chain | Residue | Details |
| A | LEU138-LEU152 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 466 |
| Details | Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 120 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 26 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 29 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
