Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000226 | biological_process | microtubule cytoskeleton organization |
A | 0000235 | cellular_component | astral microtubule |
A | 0000278 | biological_process | mitotic cell cycle |
A | 0000280 | biological_process | nuclear division |
A | 0005200 | molecular_function | structural constituent of cytoskeleton |
A | 0005515 | molecular_function | protein binding |
A | 0005525 | molecular_function | GTP binding |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0005819 | cellular_component | spindle |
A | 0005856 | cellular_component | cytoskeleton |
A | 0005874 | cellular_component | microtubule |
A | 0007017 | biological_process | microtubule-based process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0098863 | biological_process | nuclear migration by microtubule mediated pushing forces |
B | 0000022 | biological_process | mitotic spindle elongation |
B | 0000226 | biological_process | microtubule cytoskeleton organization |
B | 0000235 | cellular_component | astral microtubule |
B | 0000278 | biological_process | mitotic cell cycle |
B | 0003924 | molecular_function | GTPase activity |
B | 0005200 | molecular_function | structural constituent of cytoskeleton |
B | 0005515 | molecular_function | protein binding |
B | 0005525 | molecular_function | GTP binding |
B | 0005634 | cellular_component | nucleus |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0005856 | cellular_component | cytoskeleton |
B | 0005874 | cellular_component | microtubule |
B | 0005876 | cellular_component | spindle microtubule |
B | 0005881 | cellular_component | cytoplasmic microtubule |
B | 0007017 | biological_process | microtubule-based process |
B | 0031122 | biological_process | cytoplasmic microtubule organization |
B | 0046677 | biological_process | response to antibiotic |
B | 0046872 | molecular_function | metal ion binding |
B | 0048312 | biological_process | intracellular distribution of mitochondria |
B | 0098863 | biological_process | nuclear migration by microtubule mediated pushing forces |
B | 1903087 | biological_process | mitotic spindle pole body duplication |
K | 0003777 | molecular_function | microtubule motor activity |
K | 0005524 | molecular_function | ATP binding |
K | 0007018 | biological_process | microtubule-based movement |
K | 0008017 | molecular_function | microtubule binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue MG K 501 |
Chain | Residue |
K | LYS198 |
K | THR199 |
K | ASP360 |
K | ANP502 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue ANP K 502 |
Chain | Residue |
K | GLY197 |
K | LYS198 |
K | THR199 |
K | TYR200 |
K | LEU314 |
K | SER315 |
K | SER316 |
K | LEU361 |
K | MG501 |
K | VAL112 |
K | ARG113 |
K | GLN193 |
K | GLY195 |
K | THR196 |
site_id | AC3 |
Number of Residues | 14 |
Details | binding site for residue GDP B 501 |
Chain | Residue |
B | GLN11 |
B | CYS12 |
B | GLN15 |
B | GLU69 |
B | ASN99 |
B | SER138 |
B | GLY141 |
B | GLY142 |
B | THR143 |
B | GLY144 |
B | ASP177 |
B | ASN204 |
B | TYR222 |
B | ASN226 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue EPB B 502 |
Chain | Residue |
B | LEU215 |
B | HIS227 |
B | PHE270 |
B | PRO272 |
B | LEU361 |
site_id | AC5 |
Number of Residues | 18 |
Details | binding site for residue GTP A 500 |
Chain | Residue |
A | GLY10 |
A | GLN11 |
A | ALA12 |
A | ILE16 |
A | ASP73 |
A | ASP102 |
A | SER144 |
A | GLY147 |
A | GLY148 |
A | THR149 |
A | GLY150 |
A | THR183 |
A | GLU187 |
A | ASN210 |
A | TYR228 |
A | ASN232 |
A | ILE235 |
B | LYS252 |
Functional Information from PROSITE/UniProt
site_id | PS00227 |
Number of Residues | 7 |
Details | TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG |
Chain | Residue | Details |
A | GLY146-GLY152 | |
B | GLY140-GLY146 |
site_id | PS00228 |
Number of Residues | 4 |
Details | TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI |
Chain | Residue | Details |
B | MET1-ILE4 |
site_id | PS00411 |
Number of Residues | 12 |
Details | KINESIN_MOTOR_1 Kinesin motor domain signature. SKLhMVDLAGSE |
Chain | Residue | Details |
K | SER354-GLU365 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P68363 |
Chain | Residue | Details |
A | GLU258 | |
B | SER138 | |
B | GLY142 | |
B | THR143 | |
B | GLY144 | |
B | ASN204 | |
B | ASN226 |
site_id | SWS_FT_FI2 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:P68363 |
Chain | Residue | Details |
A | GLN11 | |
A | GLU75 | |
A | SER144 | |
A | GLY148 | |
A | THR149 | |
A | THR183 | |
A | ASN210 | |
A | ASN232 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | SITE: Involved in polymerization => ECO:0000250 |
Chain | Residue | Details |
A | TYR455 |