6S6Z

Structure of beta-Galactosidase from Thermotoga maritima

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0004565	molecular_function	beta-galactosidase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0005990	biological_process	lactose catabolic process
A	0009056	biological_process	catabolic process
A	0009341	cellular_component	beta-galactosidase complex
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0030246	molecular_function	carbohydrate binding
B	0003824	molecular_function	catalytic activity
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0004565	molecular_function	beta-galactosidase activity
B	0005975	biological_process	carbohydrate metabolic process
B	0005990	biological_process	lactose catabolic process
B	0009056	biological_process	catabolic process
B	0009341	cellular_component	beta-galactosidase complex
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0030246	molecular_function	carbohydrate binding
C	0003824	molecular_function	catalytic activity
C	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
C	0004565	molecular_function	beta-galactosidase activity
C	0005975	biological_process	carbohydrate metabolic process
C	0005990	biological_process	lactose catabolic process
C	0009056	biological_process	catabolic process
C	0009341	cellular_component	beta-galactosidase complex
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0030246	molecular_function	carbohydrate binding
D	0003824	molecular_function	catalytic activity
D	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
D	0004565	molecular_function	beta-galactosidase activity
D	0005975	biological_process	carbohydrate metabolic process
D	0005990	biological_process	lactose catabolic process
D	0009056	biological_process	catabolic process
D	0009341	cellular_component	beta-galactosidase complex
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0030246	molecular_function	carbohydrate binding
E	0003824	molecular_function	catalytic activity
E	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
E	0004565	molecular_function	beta-galactosidase activity
E	0005975	biological_process	carbohydrate metabolic process
E	0005990	biological_process	lactose catabolic process
E	0009056	biological_process	catabolic process
E	0009341	cellular_component	beta-galactosidase complex
E	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
E	0030246	molecular_function	carbohydrate binding
F	0003824	molecular_function	catalytic activity
F	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
F	0004565	molecular_function	beta-galactosidase activity
F	0005975	biological_process	carbohydrate metabolic process
F	0005990	biological_process	lactose catabolic process
F	0009056	biological_process	catabolic process
F	0009341	cellular_component	beta-galactosidase complex
F	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
F	0030246	molecular_function	carbohydrate binding
G	0003824	molecular_function	catalytic activity
G	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
G	0004565	molecular_function	beta-galactosidase activity
G	0005975	biological_process	carbohydrate metabolic process
G	0005990	biological_process	lactose catabolic process
G	0009056	biological_process	catabolic process
G	0009341	cellular_component	beta-galactosidase complex
G	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
G	0030246	molecular_function	carbohydrate binding
H	0003824	molecular_function	catalytic activity
H	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
H	0004565	molecular_function	beta-galactosidase activity
H	0005975	biological_process	carbohydrate metabolic process
H	0005990	biological_process	lactose catabolic process
H	0009056	biological_process	catabolic process
H	0009341	cellular_component	beta-galactosidase complex
H	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
H	0030246	molecular_function	carbohydrate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG A 3001

Chain	Residue
A	ALA511
A	GLY513
A	GLY575
A	GLU584
A	GLU586
A	HOH3236

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG D 3001

Chain	Residue
D	GLU584
D	GLU586
D	HOH3236
D	ALA511
D	GLY513
D	GLY575

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MG B 3001

Chain	Residue
B	ALA511
B	GLY513
B	GLY575
B	GLU584
B	GLU586
B	HOH3236

---

site_id	AC4
Number of Residues	6
Details	binding site for residue MG H 3001

Chain	Residue
H	ALA511
H	GLY513
H	GLY575
H	GLU584
H	GLU586
H	HOH3236

---

site_id	AC5
Number of Residues	6
Details	binding site for residue MG F 3001

Chain	Residue
F	ALA511
F	GLY513
F	GLY575
F	GLU584
F	GLU586
F	HOH3236

---

site_id	AC6
Number of Residues	6
Details	binding site for residue MG G 3001

Chain	Residue
G	ALA511
G	GLY513
G	GLY575
G	GLU584
G	GLU586
G	HOH3236

---

site_id	AC7
Number of Residues	6
Details	binding site for residue MG E 3001

Chain	Residue
E	ALA511
E	GLY513
E	GLY575
E	GLU584
E	GLU586
E	HOH3236

---

site_id	AC8
Number of Residues	6
Details	binding site for residue MG C 3001

Chain	Residue
C	ALA511
C	GLY513
C	GLY575
C	GLU584
C	GLU586
C	HOH3236

---

Functional Information from PROSITE/UniProt

site_id	PS00608
Number of Residues	15
Details	GLYCOSYL_HYDROL_F2_2 Glycosyl hydrolases family 2 acid/base catalyst. DKNHPSIIFWSlg.NE

Chain	Residue	Details
A	ASP427-GLU441

---

site_id	PS00719
Number of Residues	26
Details	GLYCOSYL_HYDROL_F2_1 Glycosyl hydrolases family 2 signature 1. NtVRTSHYPnqtkWYdlcDyfGLYVI

Chain	Residue	Details
A	ASN363-ILE388

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton donor => ECO:0000250

Chain	Residue	Details
A	GLU441
D	GLU441
B	GLU441
H	GLU441
F	GLU441
G	GLU441
E	GLU441
C	GLU441

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	ACT_SITE: Nucleophile => ECO:0000250

Chain	Residue	Details
A	GLU507
D	GLU507
B	GLU507
H	GLU507
F	GLU507
G	GLU507
E	GLU507
C	GLU507

---