6S6F
Crystal structure of 2-methylcitrate synthase (PrpC) from Pseudomonas aeruginosa in apo form.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019679 | biological_process | propionate metabolic process, methylcitrate cycle |
| A | 0036440 | molecular_function | citrate synthase activity |
| A | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
| A | 0050440 | molecular_function | 2-methylcitrate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019679 | biological_process | propionate metabolic process, methylcitrate cycle |
| B | 0036440 | molecular_function | citrate synthase activity |
| B | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
| B | 0050440 | molecular_function | 2-methylcitrate synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | TYR184 |
| A | GLY224 |
| A | ALA225 |
| A | ASN226 |
| A | ASP312 |
| A | THR330 |
| A | PHE333 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | ASP121 |
| A | VAL122 |
| A | GLU111 |
| A | GLN118 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 401 |
| Chain | Residue |
| B | HIS95 |
| B | ARG218 |
| B | PRO220 |
| B | THR330 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| B | HIS222 |
| B | GLY223 |
| B | GLY224 |
| B | ALA225 |
| B | ASN226 |
| B | ASP312 |
| B | THR330 |
| B | PHE333 |
| B | HOH502 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| B | HIS320 |
| B | HOH576 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 404 |
| Chain | Residue |
| B | LYS72 |
| B | GLN76 |
| B | ASP121 |
Functional Information from PROSITE/UniProt
| site_id | PS00480 |
| Number of Residues | 13 |
| Details | CITRATE_SYNTHASE Citrate synthase signature. GFGHaIy.KdsDPR |
| Chain | Residue | Details |
| A | GLY258-ARG270 |
