6S55

Crystal structure of human ATAD2 bromodomain in complex with N-(4-bromo-3-((3-methylpiperidin-1-yl)sulfonyl)phenyl)-2-(2,5-dioxoimidazolidin-1-yl)acetamide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006325	biological_process	chromatin organization
A	0006355	biological_process	regulation of transcription, DNA-templated
A	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue EDO A 1201

Chain	Residue
A	HIS998
A	GLU1091
A	GLU1092
A	ASP1094
A	HOH1309
A	HOH1400

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site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 1202

Chain	Residue
A	HOH1334
A	HOH1355
A	HOH1411
A	GLU988
A	LEU1093
A	ASP1094

---

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 1203

Chain	Residue
A	ARG1007
A	ARG1077
A	HOH1324
A	HOH1425

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site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 A 1204

Chain	Residue
A	ARG987
A	ARG990
A	ARG994
A	ARG1067
A	ARG1072
A	HOH1304
A	HOH1373

---

site_id	AC5
Number of Residues	16
Details	binding site for residue KW5 A 1205

Chain	Residue
A	ARG1007
A	VAL1008
A	PHE1009
A	LYS1011
A	PRO1012
A	VAL1013
A	ASP1014
A	GLU1017
A	VAL1018
A	TYR1021
A	MET1029
A	ILE1056
A	ALA1060
A	TYR1063
A	ASN1064
A	ILE1074

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