6S16
T. thermophilus RuvC in complex with Holliday junction substrate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004520 | molecular_function | DNA endonuclease activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006281 | biological_process | DNA repair |
| A | 0006310 | biological_process | DNA recombination |
| A | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048476 | cellular_component | Holliday junction resolvase complex |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004520 | molecular_function | DNA endonuclease activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006281 | biological_process | DNA repair |
| B | 0006310 | biological_process | DNA recombination |
| B | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048476 | cellular_component | Holliday junction resolvase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 201 |
| Chain | Residue |
| A | VAL102 |
| A | LEU166 |
| B | PRO43 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 201 |
| Chain | Residue |
| B | SER142 |
| B | HIS143 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00034, ECO:0000305|PubMed:23118486, ECO:0000305|PubMed:23980027, ECO:0000305|PubMed:31506434 |
| Chain | Residue | Details |
| A | ASP7 | |
| A | GLU70 | |
| A | HIS143 | |
| B | ASP7 | |
| B | GLU70 | |
| B | HIS143 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:23118486 |
| Chain | Residue | Details |
| A | ASP146 | |
| B | ASP146 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00034, ECO:0000269|PubMed:23118486, ECO:0000312|PDB:4EP4 |
| Chain | Residue | Details |
| A | ASP7 | |
| A | HIS143 | |
| B | ASP7 | |
| B | HIS143 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23980027, ECO:0000269|PubMed:31506434, ECO:0000312|PDB:4LD0, ECO:0000312|PDB:6S16 |
| Chain | Residue | Details |
| A | ILE10 | |
| A | PRO40 | |
| A | ARG47 | |
| A | LYS83 | |
| B | ILE10 | |
| B | PRO40 | |
| B | ARG47 | |
| B | LYS83 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00034 |
| Chain | Residue | Details |
| A | GLU70 | |
| B | GLU70 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23980027, ECO:0000269|PubMed:31506434, ECO:0000305|PubMed:23118486, ECO:0000312|PDB:4LD0 |
| Chain | Residue | Details |
| A | PHE73 | |
| B | PHE73 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23980027, ECO:0000269|PubMed:31506434, ECO:0000312|PDB:4LD0 |
| Chain | Residue | Details |
| A | ARG76 | |
| B | ARG76 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31506434, ECO:0000305|PubMed:23980027, ECO:0000312|PDB:6S16 |
| Chain | Residue | Details |
| A | LEU80 | |
| B | LEU80 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23980027, ECO:0000312|PDB:4LD0 |
| Chain | Residue | Details |
| A | MET108 | |
| A | ARG140 | |
| B | MET108 | |
| B | ARG140 |
