Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue ADP A 301 |
| Chain | Residue |
| A | GLY16 |
| A | LEU85 |
| A | LEU135 |
| A | ILE148 |
| A | ASP149 |
| A | HOH424 |
| A | HOH436 |
| A | HOH440 |
| A | HOH453 |
| A | GLY18 |
| A | ILE23 |
| A | ALA36 |
| A | LYS38 |
| A | GLU52 |
| A | TYR56 |
| A | MET82 |
| A | GLU83 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | ARG10 |
| A | LEU11 |
| A | GLY12 |
| A | LEU25 |
| A | GLY26 |
| A | THR27 |
| A | GLU34 |
| B | EDO307 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | ILE29 |
| A | GLY32 |
| B | PRO87 |
| B | GLY137 |
| B | TRP290 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | ILE15 |
| A | LEU85 |
| A | GLY86 |
| A | PRO87 |
| B | ARG10 |
| B | GLU34 |
| B | EDO306 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | PRO87 |
| A | GLY142 |
| A | TRP290 |
| A | HOH428 |
| B | ILE29 |
| B | GLY32 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | ARG98 |
| A | GLY209 |
| A | HOH434 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | GLU117 |
| A | HIS120 |
| A | SER121 |
| A | TYR156 |
| A | ARG192 |
| A | TYR266 |
| A | HOH425 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | TYR167 |
| B | LYS242 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | TYR201 |
| A | TRP213 |
| A | LYS232 |
| A | THR235 |
| A | ILE237 |
| A | HOH402 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | ASN253 |
| A | ARG256 |
| A | SER257 |
| B | ASN253 |
| B | SER257 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| A | HIS278 |
| A | PHE282 |
| A | SER283 |
| A | TYR284 |
| B | TYR284 |
| B | TYR286 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 312 |
| Chain | Residue |
| A | ASN143 |
| A | TYR286 |
| A | ASN291 |
| A | HOH428 |
| A | HOH480 |
| A | HOH490 |
| site_id | AD4 |
| Number of Residues | 18 |
| Details | binding site for residue ADP B 301 |
| Chain | Residue |
| B | SER17 |
| B | GLY18 |
| B | ILE23 |
| B | ALA36 |
| B | LYS38 |
| B | GLU52 |
| B | TYR56 |
| B | MET82 |
| B | GLU83 |
| B | LEU85 |
| B | ASP132 |
| B | LEU135 |
| B | ILE148 |
| B | ASP149 |
| B | HOH408 |
| B | HOH423 |
| B | HOH434 |
| B | HOH476 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | ILE237 |
| B | GLU238 |
| B | ASN253 |
| A | SER257 |
| A | LEU258 |
| B | PRO236 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | TYR268 |
| B | GLN271 |
| B | LEU272 |
| B | HOH414 |
| B | HOH424 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| A | ARG279 |
| B | SER267 |
| B | ARG270 |
| B | GLN271 |
| B | ARG274 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| B | TYR9 |
| B | ARG69 |
| B | TRP70 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| A | EDO304 |
| A | HOH498 |
| B | ARG10 |
| B | GLY12 |
| B | GLY26 |
| B | THR27 |
| B | GLU34 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| A | GLU34 |
| A | EDO302 |
| B | LEU85 |
| B | GLY86 |
| B | HOH407 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| B | VAL42 |
| B | ASN78 |
| B | SER101 |
| B | LYS103 |
| B | PHE282 |
| B | HOH462 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGSGSFGDIYlGtdiaagee..........VAIK |
| Chain | Residue | Details |
| A | ILE15-LYS38 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. FiHrDVKpdNFLM |
| Chain | Residue | Details |
| A | PHE124-MET136 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP128 | |
| B | ASP128 | |
| Chain | Residue | Details |
| A | ILE15 | |
| A | LYS38 | |
| B | ILE15 | |
| B | LYS38 | |
