6RTE

Dihydro-heme d1 dehydrogenase NirN in complex with DHE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006783	biological_process	heme biosynthetic process
A	0009055	molecular_function	electron transfer activity
A	0016491	molecular_function	oxidoreductase activity
A	0020037	molecular_function	heme binding
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
B	0006783	biological_process	heme biosynthetic process
B	0009055	molecular_function	electron transfer activity
B	0016491	molecular_function	oxidoreductase activity
B	0020037	molecular_function	heme binding
B	0042597	cellular_component	periplasmic space
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue HEC A 501

Chain	Residue
A	HIS12
A	GLN54
A	MET55
A	PHE58
A	LEU70
A	TYR144
A	ARG164
A	ARG312
A	HOH617
A	CYS13
A	CYS16
A	HIS17
A	PRO27
A	LEU29
A	ILE46
A	ARG50
A	THR53

---

site_id	AC2
Number of Residues	4
Details	binding site for residue BU3 A 502

Chain	Residue
A	ASP214
A	HOH646
B	ASP214
B	HOH624

---

site_id	AC3
Number of Residues	23
Details	binding site for Di-peptide HEC B 501 and CYS B 16

Chain	Residue
B	HIS12
B	CYS13
B	GLN14
B	ALA15
B	HIS17
B	GLY18
B	GLY24
B	SER25
B	GLY26
B	PRO27
B	LEU29
B	ILE46
B	ARG50
B	THR53
B	GLN54
B	MET55
B	PHE58
B	TYR144
B	ARG164
B	HOH603
B	HOH626
B	HOH664
B	HOH669

---

site_id	AC4
Number of Residues	20
Details	binding site for Di-peptide HEC B 501 and CYS B 13

Chain	Residue
B	TYR9
B	HIS12
B	GLN14
B	ALA15
B	CYS16
B	HIS17
B	PRO27
B	LEU29
B	ILE46
B	ARG50
B	THR53
B	GLN54
B	MET55
B	PHE58
B	TYR144
B	ARG164
B	HOH603
B	HOH626
B	HOH664
B	HOH669

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"description":"covalent","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"31173777","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RTD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"31173777","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RTD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31173777","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RTD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"31173777","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RTD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PubMed","id":"31173777","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RTD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31173777","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RTD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"description":"distal binding residue","evidences":[{"source":"PubMed","id":"31173777","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RTD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	354
Details	Region: {"description":"D1-heme domain","evidences":[{"source":"PubMed","id":"31173777","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---