6RSK
Cytochrome c co-crystallized with 20 eq. sulfonato-calix[8]arene and 15 eq. spermine - structure II
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005758 | cellular_component | mitochondrial intermembrane space |
| A | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| A | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0022904 | biological_process | respiratory electron transport chain |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1901612 | molecular_function | cardiolipin binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005758 | cellular_component | mitochondrial intermembrane space |
| B | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| B | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0022904 | biological_process | respiratory electron transport chain |
| B | 0046872 | molecular_function | metal ion binding |
| B | 1901612 | molecular_function | cardiolipin binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue HEC A 201 |
| Chain | Residue |
| A | ARG13 |
| A | GLY41 |
| A | TYR46 |
| A | TYR48 |
| A | THR49 |
| A | ASN52 |
| A | TRP59 |
| A | MET64 |
| A | TYR67 |
| A | LEU68 |
| A | THR78 |
| A | CYS14 |
| A | LYS79 |
| A | PHE82 |
| A | LEU94 |
| A | HOH331 |
| A | HOH334 |
| A | HOH338 |
| A | CYS17 |
| A | HIS18 |
| A | VAL28 |
| A | GLY29 |
| A | PRO30 |
| A | ILE35 |
| A | SER40 |
| site_id | AC2 |
| Number of Residues | 32 |
| Details | binding site for residue EVB A 202 |
| Chain | Residue |
| A | LYS11 |
| A | THR12 |
| A | LEU15 |
| A | GLN16 |
| A | THR19 |
| A | GLU21 |
| A | GLY24 |
| A | PRO25 |
| A | LYS27 |
| A | HIS39 |
| A | GLY41 |
| A | GLN42 |
| A | TYR46 |
| A | TYR48 |
| A | ASP50 |
| A | ILE53 |
| A | LYS54 |
| A | ASN56 |
| A | HOH303 |
| A | HOH315 |
| A | HOH316 |
| A | HOH321 |
| A | HOH345 |
| A | HOH350 |
| A | HOH352 |
| A | HOH353 |
| A | HOH354 |
| A | HOH359 |
| A | HOH374 |
| A | HOH375 |
| A | HOH382 |
| B | LYS22 |
| site_id | AC3 |
| Number of Residues | 26 |
| Details | binding site for residue EVB A 203 |
| Chain | Residue |
| A | ALA-1 |
| A | GLY1 |
| A | ALA3 |
| A | LYS4 |
| A | LYS4 |
| A | LYS5 |
| A | THR8 |
| A | THR96 |
| A | TYR97 |
| A | LYS99 |
| A | LYS100 |
| A | SPM211 |
| A | SPM212 |
| A | HOH305 |
| A | HOH305 |
| A | HOH306 |
| A | HOH310 |
| A | HOH311 |
| A | HOH337 |
| A | HOH343 |
| A | HOH344 |
| A | HOH347 |
| A | HOH359 |
| A | HOH361 |
| A | HOH362 |
| A | HOH368 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue EVB A 204 |
| Chain | Residue |
| A | ASN70 |
| A | LYS72 |
| A | LYS73 |
| A | LYS79 |
| A | MET80 |
| A | ALA81 |
| A | PHE82 |
| A | GLY83 |
| A | SO4206 |
| A | HOH336 |
| B | EVB203 |
| B | SPM210 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 205 |
| Chain | Residue |
| A | HOH329 |
| A | ARG13 |
| A | GLY84 |
| A | LEU85 |
| A | LYS86 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 206 |
| Chain | Residue |
| A | ARG13 |
| A | ALA81 |
| A | PHE82 |
| A | GLY83 |
| A | EVB204 |
| A | HOH349 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 207 |
| Chain | Residue |
| A | ASN70 |
| A | LYS86 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 208 |
| Chain | Residue |
| A | GLU-4 |
| A | GLU88 |
| A | ARG91 |
| A | HOH342 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 209 |
| Chain | Residue |
| A | LYS55 |
| A | HOH333 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 210 |
| Chain | Residue |
| A | GLU21 |
| A | LYS22 |
| A | HOH309 |
| A | HOH312 |
| A | HOH357 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue SPM A 211 |
| Chain | Residue |
| A | EVB203 |
| A | HOH328 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue SPM A 212 |
| Chain | Residue |
| A | EVB203 |
| site_id | AD4 |
| Number of Residues | 24 |
| Details | binding site for residue EVB B 202 |
| Chain | Residue |
| A | LYS22 |
| B | LYS11 |
| B | LEU15 |
| B | GLN16 |
| B | THR19 |
| B | GLU21 |
| B | GLY24 |
| B | PRO25 |
| B | LYS27 |
| B | HIS39 |
| B | GLY41 |
| B | GLN42 |
| B | TYR46 |
| B | SER47 |
| B | TYR48 |
| B | ASP50 |
| B | ILE53 |
| B | LYS54 |
| B | ASN56 |
| B | HOH303 |
| B | HOH310 |
| B | HOH313 |
| B | HOH324 |
| B | HOH328 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for residue EVB B 203 |
| Chain | Residue |
| A | EVB204 |
| B | ASN70 |
| B | LYS72 |
| B | MET80 |
| B | ALA81 |
| B | PHE82 |
| B | GLY83 |
| B | SO4206 |
| B | SPM210 |
| B | HOH326 |
| B | HOH327 |
| site_id | AD6 |
| Number of Residues | 10 |
| Details | binding site for residue EVB B 204 |
| Chain | Residue |
| B | ALA-1 |
| B | GLY1 |
| B | ALA3 |
| B | LYS4 |
| B | ALA7 |
| B | THR96 |
| B | TYR97 |
| B | LYS100 |
| B | SPM211 |
| B | HOH317 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 205 |
| Chain | Residue |
| B | ARG13 |
| B | GLY84 |
| B | LYS86 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 206 |
| Chain | Residue |
| B | ARG13 |
| B | PHE82 |
| B | GLY83 |
| B | GLY84 |
| B | EVB203 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 207 |
| Chain | Residue |
| B | GLU21 |
| B | LYS22 |
| B | HOH305 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 B 208 |
| Chain | Residue |
| B | SPM211 |
| site_id | AE2 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 B 209 |
| Chain | Residue |
| B | LYS55 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue SPM B 210 |
| Chain | Residue |
| A | EVB204 |
| B | EVB203 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue SPM B 211 |
| Chain | Residue |
| B | EVB204 |
| B | SO4208 |
| site_id | AE5 |
| Number of Residues | 25 |
| Details | binding site for Di-peptide HEC B 201 and CYS B 17 |
| Chain | Residue |
| B | ARG13 |
| B | CYS14 |
| B | LEU15 |
| B | GLN16 |
| B | HIS18 |
| B | LYS27 |
| B | VAL28 |
| B | GLY29 |
| B | ILE35 |
| B | SER40 |
| B | GLY41 |
| B | TYR46 |
| B | TYR48 |
| B | THR49 |
| B | ASN52 |
| B | TRP59 |
| B | TYR67 |
| B | LEU68 |
| B | THR78 |
| B | LYS79 |
| B | PHE82 |
| B | LEU94 |
| B | HOH304 |
| B | HOH306 |
| B | HOH314 |
| site_id | AE6 |
| Number of Residues | 24 |
| Details | binding site for Di-peptide HEC B 201 and CYS B 14 |
| Chain | Residue |
| B | PHE10 |
| B | ARG13 |
| B | LEU15 |
| B | GLN16 |
| B | CYS17 |
| B | HIS18 |
| B | VAL28 |
| B | ILE35 |
| B | SER40 |
| B | GLY41 |
| B | TYR46 |
| B | TYR48 |
| B | THR49 |
| B | ASN52 |
| B | TRP59 |
| B | TYR67 |
| B | LEU68 |
| B | THR78 |
| B | LYS79 |
| B | PHE82 |
| B | LEU94 |
| B | HOH304 |
| B | HOH306 |
| B | HOH314 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CX5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CX5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6,N6,N6-trimethyllysine; by CTM1","evidences":[{"source":"PubMed","id":"10791961","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"source":"PubMed","id":"10821864","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
