6RP5
Crystal structure of monocarboxylated hemoglobin from the sub-Antarctic fish Eleginops maclovinus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005833 | cellular_component | hemoglobin complex |
| A | 0015671 | biological_process | oxygen transport |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0031720 | molecular_function | haptoglobin binding |
| A | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0043177 | molecular_function | organic acid binding |
| A | 0072562 | cellular_component | blood microparticle |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005344 | molecular_function | oxygen carrier activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0005833 | cellular_component | hemoglobin complex |
| B | 0015671 | biological_process | oxygen transport |
| B | 0019825 | molecular_function | oxygen binding |
| B | 0020037 | molecular_function | heme binding |
| B | 0031720 | molecular_function | haptoglobin binding |
| B | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0043177 | molecular_function | organic acid binding |
| B | 0072562 | cellular_component | blood microparticle |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CMO A 201 |
| Chain | Residue |
| A | VAL63 |
| A | HEM202 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue HEM A 202 |
| Chain | Residue |
| A | HIS88 |
| A | LEU92 |
| A | VAL94 |
| A | ASN98 |
| A | LEU102 |
| A | LEU137 |
| A | CMO201 |
| A | HOH310 |
| A | HOH319 |
| B | TYR49 |
| A | MET32 |
| A | TYR42 |
| A | PHE43 |
| A | HIS45 |
| A | TRP46 |
| A | THR62 |
| A | LEU84 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 203 |
| Chain | Residue |
| A | TRP46 |
| A | HIS59 |
| A | HOH310 |
| B | ASN50 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 204 |
| Chain | Residue |
| A | VAL56 |
| A | LYS57 |
| A | ALA58 |
| A | HOH367 |
| B | SER13 |
| B | HOH354 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue DTN A 205 |
| Chain | Residue |
| A | PRO51 |
| A | GLY52 |
| A | HOH401 |
| B | ASN123 |
| B | PRO124 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CMO B 201 |
| Chain | Residue |
| B | HIS63 |
| B | VAL67 |
| B | HEM202 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue HEM B 202 |
| Chain | Residue |
| B | HIS41 |
| B | LYS59 |
| B | HIS63 |
| B | LEU91 |
| B | HIS92 |
| B | LEU96 |
| B | PHE103 |
| B | LEU141 |
| B | CMO201 |
| B | HOH312 |
| B | HOH325 |
| B | HOH403 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | binding site for residue SO4 B 203 |
| Chain | Residue |
| B | GLY43 |
| B | SER44 |
| B | PHE45 |
| B | GLY46 |
| B | ASN57 |
| B | LYS59 |
| B | HOH314 |
| B | HOH317 |
| B | HOH318 |
| B | HOH362 |
| B | HOH388 |
| B | HOH402 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 204 |
| Chain | Residue |
| A | LYS57 |
| B | SER17 |
| B | LYS117 |
| B | MET118 |
| B | HOH302 |
| B | HOH338 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23086282","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"proximal binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23086282","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PDB","id":"4ESA","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"distal binding residue","evidences":[{"source":"PubMed","id":"23086282","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"proximal binding residue","evidences":[{"source":"PubMed","id":"23086282","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
